Zarzissine
Zarzissine exhibits cytotoxicity against three human and murine tumor cell lines.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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J Pharmacopuncture.2023, 26(4):357-365.
TCI CO.2019, US20190151257A1
J Korean Med Ophthalmol Otolaryngol Dermatol2023, 36(1):1-20.
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Malaysian Journal of Analytical Sciences2023, 27(4):840-848.
Biomed Pharmacother.2022, 145:112474.
Current Traditional Medicine, 2021, 7:326-335(10).
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J Nat Prod. 1994 Oct;57(10):1455-7.
Zarzissine, a new cytotoxic guanidine alkaloid from the Mediterranean sponge Anchinoe paupertas.[Pubmed:
7807130]
METHODS AND RESULTS:
From a CH2Cl2 extract of the Mediterranean sponge Anchinoe paupertas were isolated and characterized Zarzissine [2], a new 4,5-guanidino-pyridazine compound and the known p-hydroxybenzaldehyde [1]. The structure of Zarzissine [2] was elucidated by spectroscopic methods, including the application of a number of 2D nmr techniques.
CONCLUSIONS:
Biological activities of compounds 1 and 2 were also determined, with Zarzissine exhibiting cytotoxicity against three human and murine tumor cell lines.
Zhongguo Zhong Yao Za Zhi. 2013 Jan;38(2):204-7.
Chemical constitunents of seeds of Oroxylum indicum.[Pubmed:
23672042]
To study the chemical constituents in the seeds of Oroxylum indicum.
METHODS AND RESULTS:
Twenty compounds were isolated and purified by silica gel, and Sephadex LH-20 column chromatography, and their structures were determined by spectroscopic analysis including NMR and MS. Twenty compounds were isolated and identified as oroxin A (1), oroxin B (2), chrysin (3), baicalein (4), quercetin (5), apigenin (6), kaempferol (7), quercetin-3-O-ara-binopyranoside (8), lupeol C9), lup-20 (29)-ene-2alpha,3beta-diol (10), pinosylvin (11), dihydropinosylvin (12), cholest-5-ene-3, 7-diol (13), rengyol (14), isorengyol (15), Zarzissine (16), (E) -pinosylvin-3-O-beta-D-glucopyranoside (17), adenosine (18), sitosterol (19) and daucosterol (20).
CONCLUSIONS:
Compounds 11-13 and 15-18 were obtained from the genus Oroxylum for the first time, and except compound 18, the remaining 6 compounds were obtained from the family Bignoniaceae for the first time.
