Vogeloside shows inhibition of nitric oxide production in lipopolysaccharide-activated macrophages; its activity is comparable to that of aminoguanidine, a classic inhibitor.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Phytochemistry. 2006 Jul;67(14):1534-8.
Modified secoiridoid from Acicarpha tribuloides and inhibition of nitric oxide production in LPS-activated macrophages.[Pubmed: 16808936
METHODS AND RESULTS:
Bioassay-guided fractionation of Acicarpha tribuloides Juss. resulted in the isolation of an uncommon non-glycosylated secoiridoid, tribulolide (1), two known secoiridoid glycosides named secologanic acid (2) and Vogeloside (3) as well as two natural chromones, 6,7-dimethoxychromone (4) and 7-hydroxy-6-methoxy-chromone (5).
Compounds 1-3 showed inhibition of nitric oxide production in lipopolysaccharide-activated macrophages; their activity is comparable to that of aminoguanidine, a classic inhibitor.
Zhongguo Zhong Yao Za Zhi. 2007 Dec;32(24):2606-9.
Terpenoid glycosides from stem of Luculia pinceana.[Pubmed: 18338598
To study the chemical constituents from n-BuOH portion of ethanolic extract from the stem of Luculia pinceana.
METHODS AND RESULTS:
The column chromatographic techniques were applied to isolate constituents. A combination of IR, FAB-MS, NMR and 2D NMR spectroscopy was used to identify structures.
Seven compounds were isolated from the n-BuOH fraction and their structures were elucidated as Vogeloside (1), epi-Vogeloside (2), loganoside (3), loganin (4), cincholic acid 28-O-beta-D-glucopyranosyl ester (5), cincholic acid-3-O-beta-D-glucopyranoside, 28-O-beta-D-glucopyranosyl ester (6), cincholic acid-3-O-beta-D-glucopyranoside (7).
Compounds 1-7 were isolated from the genus for the first time.