Vogeloside

Phytochemistry. 2006 Jul;67(14):1534-8.

Modified secoiridoid from Acicarpha tribuloides and inhibition of nitric oxide production in LPS-activated macrophages.[Pubmed: 16808936]

METHODS AND RESULTS:
Bioassay-guided fractionation of Acicarpha tribuloides Juss. resulted in the isolation of an uncommon non-glycosylated secoiridoid, tribulolide (1), two known secoiridoid glycosides named secologanic acid (2) and Vogeloside (3) as well as two natural chromones, 6,7-dimethoxychromone (4) and 7-hydroxy-6-methoxy-chromone (5).
CONCLUSIONS:
Compounds 1-3 showed inhibition of nitric oxide production in lipopolysaccharide-activated macrophages; their activity is comparable to that of aminoguanidine, a classic inhibitor.

Zhongguo Zhong Yao Za Zhi. 2007 Dec;32(24):2606-9.

Terpenoid glycosides from stem of Luculia pinceana.[Pubmed: 18338598]

To study the chemical constituents from n-BuOH portion of ethanolic extract from the stem of Luculia pinceana.
METHODS AND RESULTS:
The column chromatographic techniques were applied to isolate constituents. A combination of IR, FAB-MS, NMR and 2D NMR spectroscopy was used to identify structures. Seven compounds were isolated from the n-BuOH fraction and their structures were elucidated as Vogeloside (1), epi-Vogeloside (2), loganoside (3), loganin (4), cincholic acid 28-O-beta-D-glucopyranosyl ester (5), cincholic acid-3-O-beta-D-glucopyranoside, 28-O-beta-D-glucopyranosyl ester (6), cincholic acid-3-O-beta-D-glucopyranoside (7).
CONCLUSIONS:
Compounds 1-7 were isolated from the genus for the first time.