Tecomin
Tecomin is a potential bioactive compound from the flowers of Trollius chinensis, it was easily absorbed and rapidly metabolized into veratric acid in vivo , and then the latter was eliminated slowly.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Chemistry of Natural Compounds2018, 204-206
J Cell Mol Med.2023, 27(11):1592-1602.
SBRAS2016, 12
Int J Mol Sci.2020, 21(24):9369.
J Appl Biol Chem.2024, 67:33,238-244
The Pharmaceutical Society of Japan2018, 138(4):571-579
J Sep Sci.2022, 45(18):3556-3566.
Front Pharmacol.2021, 12:635510.
Natural Product Communications2023, 18(9).
Oxid Med Cell Longev.2022, 2022:9139338.
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Biomed Chromatogr. 2016 Apr;30(4):612-7.
Pharmacokinetics of tecomin in rats after intragastric and intravenous administration[Pubmed:
26317973]
METHODS AND RESULTS:
The pharmacokinetics of Tecomin, which is a potential bioactive compound from the flowers of Trollius chinensis , was studied.
CONCLUSIONS:
The results showed that this compound was easily absorbed and rapidly metabolized into veratric acid in vivo , and then the latter was eliminated slowly. In addition, the simulant in vitro gastrointestinal transformation experiments demonstrated that the basic enteral environment and intestinal bacterial flora also contributed to the metabolism of Tecomin to veratric acid.
