Taiwanhomoflavone B

Taiwanhomoflavone B
Product Name Taiwanhomoflavone B
CAS No.: 509077-91-2
Catalog No.: CFN98808
Molecular Formula: C32H24O10
Molecular Weight: 568.5 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Yellow powder
Source: The barks of Cephalotaxus fortunei
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Taiwanhomoflavone B is cytotoxic with ED(50) values of 3.8 and 3.5 microg/ml, against KB oral epidermoid carcinoma and Hepa-3B hepatoma cells, respectively.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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  • Org Biomol Chem.2017, 15(31):6483-6492
  • Phytomedicine.2022, 100:154085.
  • Processes2021, 9(1), 153;
  • Int J Mol Sci.2023, 24(8):7045.
  • Dis Markers.2022, 2022:2380879.
  • Metabolites.2019, 9(11):E271
  • Front Endocrinol (Lausanne).2023, 14:1138676.
  • Antimicrob Agents Chemother.2020, AAC.01921-20.
  • ACS Pharmacol. Transl. Sci.2022, 5,7,479-490
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    Chem Pharm Bull (Tokyo). 2002 Dec;50(12):1607-8.
    A novel cytotoxic C-methylated biflavone, taiwanhomoflavone-B from the twigs of Cephalotaxus wilsoniana.[Pubmed: 12499600 ]

    METHODS AND RESULTS:
    A novel C-methylated biflavone, Taiwanhomoflavone B (1), together with known compounds, 7,4',7"-tri-O-methylamentoflavone, 6-C-methylnaringenin and apigenin-7-O-beta-glucoside were isolated from an ethanolic extract of Cephalotaxus wilsoniana. The structure of Taiwanhomoflavone B was elucidated on the basis of spectroscopic analysis.
    CONCLUSIONS:
    Taiwanhomoflavone B is cytotoxic with ED(50) values of 3.8 and 3.5 microg/ml, against KB oral epidermoid carcinoma and Hepa-3B hepatoma cells, respectively.
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