Stilbostemin B
Stilbostemin A, stilbostemin B , stilbostemin D , stilbostemin F , and stilbostemin G
show structure-dependent inhibition of leukotriene biosynthesis with IC(50) values ranging from 3.7 to >50 microM.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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J Nat Prod. 2005 Jan;68(1):83-5.
Inhibition of leukotriene biosynthesis by stilbenoids from Stemona species.[Pubmed:
15679323 ]
METHODS AND RESULTS:
Fifteen stilbenoids and two alkaloids from Stemona collinsae, S. tuberosa, and S. peirrei were tested alongside the commercially available stilbenoids resveratrol and pinosylvin for inhibition of leukotriene formation in an ex vivo test system based on activated human neutrophilic granulocytes.
CONCLUSIONS:
The stilbenoids resveratrol (1), pinosylvin (2), dihydropinosylvin (3), stilbostemin A (4), Stilbostemin B (5), stilbostemin D (6), stilbostemin F (7), stilbostemin G (8), stemofuran B (9), stemofuran C (10), stemofuran D (11), stemofuran G (12), stemofuran J (13), stemanthrene A (14), stemanthrene B (15), stemanthrene C (16), and stemanthrene D (17) showed structure-dependent activities with IC(50) values ranging from 3.7 to >50 microM.
The alkaloids tuberostemonine (18) and neotuberostemonine (19) were inactive at a concentration of 50 microM.
Zhongguo Zhong Yao Za Zhi. 2014 Feb;39(4):695-8.
Chemical constituents from Glechoma longituba.[Pubmed:
25204149]
Fourteen compounds were obtained from Glechoma longituba by the chromatographic methods of silica gel,ODS,Sephadex LH-20 and preparative of HPLC.
METHODS AND RESULTS:
According to physicochemical properties and spectral data,these compounds were identified as Stilbostemin B(l),trilepisiumic acid(2),3,4-dihydroxyphenyl ethanol ketone(3),bergeninmonohydrate(4),oresbiusin A(5),norbergenin(6),stilbostemin D(7),ehretioside B(8),ethyl ferulate(9),E-p-hydroxy-cinnamic acid(10),methyl gallate(ll),protocalechuic acid(12),4'-Hydroxyacetophenone(13),and E-3-2,4-dihydroxyphenyl-2-acrylic acid(14).
CONCLUSIONS:
Among them,compounds1-10,13 and 14 were isolated from this plant for the first time.
