Schizanrin L
Schizanrin L is a natural product from Kadsura coccinea.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Chemistry of Natural Compounds2018, 204-206
ACS Synth Biol.2022, 11(10):3296-3304.
Front Pharmacol.2021, 12:635510.
Front Endocrinol (Lausanne).2020, 11:568436.
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Food Funct.2024, 15(8):4262-4275.
Sci. Rep.2015, 14-23
Braz J Med Biol Res. 2016, 49(7)
Nutrients.2021, 13(12):4364.
Heliyon.2024, 10(11):e32352.
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Planta Med. 2005 Jul;71(7):646-53.
Antihepatitis activity (anti-HBsAg and anti-HBeAg) of C19 homolignans and six novel C18 dibenzocyclooctadiene lignans from Kadsura japonica.[Pubmed:
16041651 ]
METHODS AND RESULTS:
Bioassay-directed fractionation of the EtOAc extract of Kadsura japonica has led to the isolation of six new C18 dibenzocyclooctadiene lignans, schizanrin I, schizanrin J, schizanrin K, Schizanrin L, schizanrin M, schizanrin N, along with four known C19 homolignans, taiwanschirins A, B, C, and heteroclitin F. The elucidations of the new structures were based on spectral analysis.
CONCLUSIONS:
Bioassay evaluation against human type B hepatitis revealed that taiwanschirins A and B showed strong activity for anti-HBsAg and a medium effect for anti-HBeAg at 25 microg/mL (12.9 and 11.9 microM for taiwanschirins A and B, respectively).
