Orobanone
Orobanone shows antibacterial activities against Bacillus cereus.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
J Inflamm Res.2022, 15:5347-5359.
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Int J Mol Sci.2022, 23(13):7115.
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Front Pharmacol.2023, 14:1095083.
Molecules2022, 27(12):3824.
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Nat Prod Sci. 2015 Sep;21(3):147-149.
Antibiotic components from the rhizomes of Curcuma zedoaria[Reference:
WebLink]
METHODS AND RESULTS:
Two terpenoids, including one uniquely aromatized one (1), were isolated from CH2Cl2-soluble fraction of MeOH extracts of Curcuma zedoaria. They were identified to be a sesquiterpene ketolactone (1) and Orobanone (2), respectively on the basis of their NMR data. The structure of compound 1 was confirmed by X-ray chrystallography and the reported NMR assignments for 1 were revised in this study. Antibiotic activities for compounds 1 and 2 were evaluated using disk diffusion assay.
CONCLUSIONS:
Compound 1 showed potent antibacterial activities against Listeria monocytogenes and Staphylococcus pseudointermedius while compound 2 was active against Bacillus cereus.
Phytochemistry.1981;20(4):777–779.
A tropone derivative from orobanche rapum-genistae.[Reference:
WebLink]
METHODS AND RESULTS:
A new tropone,3,8-dimethyl-5-isopropyl-2,3- dihydro(1H)azulen-6-one, named Orobanone, has been isolated for the first time from a plant (Orobanche rapum-genistae, Orobanchaceae). This tropone is synthesized by the parasite and exists, with other related compounds, in various species of broom-rapes.
Pharmazie. 2009 May;64(5):350-1.
Pernambucone, a new tropone derivative from Croton argyroglossum.[Pubmed:
19530449]
METHODS AND RESULTS:
Two tropone derivatives, Orobanone (1), previously isolated from Orobanche rapum-genistae, and the new natural product pernambucone (3,8-dimethyl-5-isopropyl-2,3-dihydro-1H-azulene-1,6-dione, 2), were isolated from the sterm bark of Croton argyroglossum. The structures were elucidated from spectroscopic data.
