Procurcumenol

Procurcumenol
Product Name Procurcumenol
CAS No.: 21698-40-8
Catalog No.: CFN92647
Molecular Formula: C15H22O2
Molecular Weight: 234.3 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Powder
Targets: TNF-α | NO
Source: The rhizomes of Curcuma phaeocaulis.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $388/5mg
Procurcumenol is an inhibitor of Nitric Oxide. Procurcumenol and epicurcumenol have inhibitory effects on release of tumor necrosis factor-a (TNF-a).
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Pharmacogn Mag.2015, 11:S585-91
  • Vojnosanit Pregl2016, 75(00):391-391
  • Molecules.2021, 26(12):3652.
  • Applied Biological Chemistry2020, 63:37.
  • Front Pharmacol.2022, 13:883475.
  • Molecules.2019, 24(4):E744
  • Evid Based Complement Alternat Med.2017, 2017:1401279
  • Pharmaceutics.2023, 15(6):1771.
  • Separations2023, 10(4),255.
  • Eur J Pharmacol.2024, 963:176280.
  • Torilolone

    Catalog No: CFN96368
    CAS No: 13018-09-2
    Price: Inquiry(manager@chemfaces.com)
    8-O-Acetyltorilolone

    Catalog No: CFN96792
    CAS No: 20482-21-7
    Price: Inquiry(manager@chemfaces.com)
    Torilin

    Catalog No: CFN96316
    CAS No: 13018-10-5
    Price: Inquiry(manager@chemfaces.com)
    1alpha-Hydroxytorilin

    Catalog No: CFN96357
    CAS No: 887147-75-3
    Price: Inquiry(manager@chemfaces.com)
    1beta-Hydroxytorilin

    Catalog No: CFN96793
    CAS No: 509078-16-4
    Price: Inquiry(manager@chemfaces.com)
    Sugetriol 6,9-diacetate

    Catalog No: CFN96652
    CAS No: 17928-63-1
    Price: Inquiry(manager@chemfaces.com)
    Curcumenol

    Catalog No: CFN92614
    CAS No: 19431-84-6
    Price: $70/20mg
    Isocurcumenol

    Catalog No: CFN92618
    CAS No: 24063-71-6
    Price: $238/20mg
    Curcumol

    Catalog No: CFN99187
    CAS No: 4871-97-0
    Price: $40/20mg
    4beta,12-dihydroxyguaian-6,10-diene

    Catalog No: CFN90947
    CAS No: 461644-90-6
    Price: $268/5mg
    J Nat Prod. 2013 Feb 22;76(2):223-9.
    Sesquiterpenes from the rhizomes of Curcuma heyneana.[Pubmed: 23387824]

    METHODS AND RESULTS:
    Four new germacranes [heyneanones A-D (1-4)], three new guaianes [4,10-epizedoarondiol (5), 15-hydroxyProcurcumenol (6), 12-hydroxycurcumenol (7)], and two new spirolactones [curcumanolides C (8) and D (9)] were isolated from the rhizomes of Curcuma heyneana together with 13 known sesquiterpenes and two known labdane-type diterpenes.
    CONCLUSIONS:
    Among the isolated compounds, heyneanone A (1), heyneanone C (3), 4,10-epizedoarondiol (5), Procurcumenol (16), aerugidiol (17), zerumin A (23), and (E)-15,16-bisnorlabda-8(17),11-dien-13-one (24) inhibited protein tyrosine phosphatase 1B (PTP1B) with IC(50) values of 42.5, 35.2, 35.1, 45.6, 35.7, 10.4, and 14.7 μM, respectively.
    ScientificWorldJournal. 2014;2014:321943.
    Cytotoxic constituents from the rhizomes of Curcuma zedoaria.[Pubmed: 25126594]
    Curcuma zedoaria also known as Temu putih is traditionally used in food preparations and treatment of various ailments including cancer.
    METHODS AND RESULTS:
    The cytotoxic activity of hexane, dichloromethane, ethyl acetate, methanol, and the methanol-soxhlet extracts of Curcuma zedoaria rhizomes was tested on two human cancer cell lines (Ca Ski and MCF-7) and a noncancer cell line (HUVEC) using MTT assay. Investigation on the chemical components in the hexane and dichloromethane fractions gave 19 compounds, namely, labda-8(17),12 diene-15,16 dial (1), dehydrocurdione (2), curcumenone (3), comosone II (4), curcumenol (5), Procurcumenol (6), germacrone (7), zerumbone epoxide (8), zederone (9), 9-isopropylidene-2,6-dimethyl-11-oxatricyclo[6.2.1.0(1,5)]undec-6-en-8-ol (10), furanodiene (11), germacrone-4,5-epoxide (12), calcaratarin A (13), isoProcurcumenol (14), germacrone-1,10-epoxide (15), zerumin A (16), curcumanolide A (17), curcuzedoalide (18), and gweicurculactone (19). Compounds (1-19) were evaluated for their antiproliferative effect using MTT assay against four cancer cell lines (Ca Ski, MCF-7, PC-3, and HT-29).
    Carasinol D

    Catalog No: CFN95044
    CAS No: 1072797-66-0
    Price: $333/5mg
    Gancaonin N

    Catalog No: CFN95066
    CAS No: 129145-52-4
    Price: $463/5mg
    Yuanhuanin

    Catalog No: CFN95127
    CAS No: 83133-14-6
    Price: $318/5mg
    Leachianol G

    Catalog No: CFN95146
    CAS No: 164204-62-0
    Price: $368/5mg
    Momordicoside X

    Catalog No: CFN95170
    CAS No: 1333321-50-8
    Price: $368/5mg
    Platycogenin A

    Catalog No: CFN95240
    CAS No: 1459719-53-9
    Price: $388/5mg
    5,6,7,3',4',5'-Hexamethoxyflavanone

    Catalog No: CFN95376
    CAS No: 74064-17-8
    Price: $318/10mg
    New compound 16

    Catalog No: CFN95465
    CAS No: N/A
    Price: $413/5mg
    4-O-Coumaroylquinic acid

    Catalog No: CFN95508
    CAS No: 53539-37-0
    Price: $318/5mg
    12-Acetoxy ganoderic acid D

    Catalog No: CFN95535
    CAS No: N/A
    Price: $318/5mg