Guaiol
(-)-Guaiol is a biocatalyst. Guaiol has insecticidal activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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United States Patent Application2020, 20200038363
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Nat Chem Biol.2018, 14(8):760-763
Toxicological Research2020, doi: 10.1007.
Journal of Functional Foods2019, 52:430-441
Trop J Pharm Res.2023, 22(3):283-288.
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Nat Prod Commun. 2013 Oct;8(10):1353-4.
Guaiol--a naturally occurring insecticidal sesquiterpene.[Pubmed:
24354171]
The dichloromethane fraction of Ferula ferulaeoides was analyzed by GC and GC-MS, and thirty-four compounds were identified.
METHODS AND RESULTS:
The main component in the fraction, Guaiol (37.0%) was separated by chromatographic methods and identified from spectroscopic data, including 1H and 13C NMR, and X-ray crystallographic diffraction. Guaiol showed significant inhibition of aphids at a concentration of 70 mg/L. It also showed good contact activities against the 4th instar larvae of Mythimna separate and 3rd instar larvae of Plutella xylostella, with LD50 values of 0.07 and 8.9 mg/larva, as well as fumigation activity against the 4th instar larvae ofM. separata and adult Musca domestica, with LC50 values of 3.5 microL/L and 16.9 microL/L, respectively.
Nat Prod Res. 2006 Jul 10;20(8):731-4.
Biotransformation of (-)-guaiol by Eurotium rubrum as a biocatalyst.[Pubmed:
16753905]
METHODS AND RESULTS:
The biotransformation of (-)-Guaiol (1) has been investigated by using plant parasite fungus, Eurotium rubrum. Compound 1 was oxidized at the C-2 position, and transformed to pancherione.
