Olean-12-ene-3,24-diol

Olean-12-ene-3,24-diol
Product Name Olean-12-ene-3,24-diol
CAS No.: 119318-15-9
Catalog No.: CFN99305
Molecular Formula: C30H50O2
Molecular Weight: 442.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The herbs of Phyllanthus flexuosus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • In Vitro Cellular & Developmental Biology - Plant 2021, 57:874¨C882.
  • Life Sci.2018, 209:498-506
  • Mol Cells.2015, 38(9):765-72
  • J Cell Biochem.2022, 123(7):1222-1236.
  • Planta Med.2023, a-2192-2281.
  • Separations2021, 8(6),80.
  • BMB Rep.2020, 53(4):218-222.
  • Enzyme Microb Technol.2019, 122:64-73
  • Toxicol In Vitro.2023, 86:105521.
  • Food Sci Biotechnol.2023, 32(7):997-1003.
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    Identification of β‐amyrin and sophoradiol 24‐hydroxylase by expressed sequence tag mining and functional expression assay.[Reference: WebLink]
    Triterpenes exhibit a wide range of structural diversity produced by a sequence of biosynthetic reactions. Cyclization of oxidosqualene is the initial origin of structural diversity of skeletons in their biosynthesis, and subsequent regio- and stereospecific hydroxylation of the triterpene skeleton produces further structural diversity. The enzymes responsible for this hydroxylation were thought to be cytochrome P450-dependent monooxygenase, although their cloning has not been reported.
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