(+)-Nortrachelogenin

(+)-Nortrachelogenin
Product Name (+)-Nortrachelogenin
CAS No.: 61521-74-2
Catalog No.: CFN96714
Molecular Formula: C20H22O7
Molecular Weight: 374.38 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Targets: HIV | Antifection
Source: The roots of Wikstroemia indica.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
(+)-Nortrachelogenin is moderately active against HIV-1 in vitro; it also can induce morphological deformation of P. oryzae mycelia with the MMDC value of 31.3 +/- 1.8 microM. (+)-Nortrachelogenin shows effects on the central nervous system producing depression in rabbits.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Foods.2022, 12(1):136.
  • Molecules.2019, 24(20):3755
  • bioRxiv-Pharm.&Toxi.2022, 2022.481203.
  • J Korean Soc Food Sci Nutr2020, doi: 10.3746.
  • J Sep Sci.2019, 42(21):3352-3362
  • Planta Medica International2022, 9(01):e108-e115.
  • Acta horticulturae2017, 1158:257-268
  • Metabolites2023, 13(1), 3.
  • Front Microbiol.2023, 14:1232039.
  • Aging (Albany NY).2021, 13(19):22867-22882.
  • Nortrachelogenin-8'-O-beta-glucoside

    Catalog No: CFN95234
    CAS No: 858127-38-5
    Price: $368/10mg
    Nortrachelogenin-5'-C-beta-glucoside

    Catalog No: CFN95251
    CAS No: 858127-39-6
    Price: $318/10mg
    Traxillaside

    Catalog No: CFN96608
    CAS No: 149415-62-3
    Price: Inquiry(manager@chemfaces.com)
    Trachelosiaside

    Catalog No: CFN89466
    CAS No: 106647-12-5
    Price: Inquiry(manager@chemfaces.com)
    Styraxlignolide F

    Catalog No: CFN92491
    CAS No: 823214-06-8
    Price: Inquiry(manager@chemfaces.com)
    2,3-Bis(3,4-dimethoxybenzyl)butyrolactone

    Catalog No: CFN98281
    CAS No: 25488-59-9
    Price: Inquiry(manager@chemfaces.com)
    Tupichilignan A

    Catalog No: CFN97182
    CAS No: 69586-96-5
    Price: Inquiry(manager@chemfaces.com)
    5-Acetoxymatairesinol dimethyl ether

    Catalog No: CFN97230
    CAS No: 74892-45-8
    Price: Inquiry(manager@chemfaces.com)
    Pluviatolide

    Catalog No: CFN92059
    CAS No: 28115-68-6
    Price: Inquiry(manager@chemfaces.com)
    Kaerophyllin

    Catalog No: CFN97234
    CAS No: 75590-33-9
    Price: Inquiry(manager@chemfaces.com)
    Lloydia. 1979 Mar-Apr;42(2):159-62.
    (+)Nortrachelogenin, a new pharmacologically active lignan from Wikstroemia indica.[Pubmed: 449625]

    METHODS AND RESULTS:
    A new lignan, (+)-Nortrachelogenin (I), and a known compound, daphnoretin were isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae).
    CONCLUSIONS:
    The structure of (+)-Nortrachelogenin was established as 8(R)8'-4,4',8'-trihydroxy-3,3'-dimethoxylignan-olid, (9,9') on the basis of spectroscopic evidence and comparison with its enantiomer, (-)-nortrachelogenin. +-nortrachelogenin(I) showed effects on the central nervous system producing depression in rabbits.
    Planta Med. 2000 Aug;66(6):564-7.
    Antifungal, antimitotic and anti-HIV-1 agents from the roots of Wikstroemia indica.[Pubmed: 10985087]

    METHODS AND RESULTS:
    With guidance of Pyricularia oryzae bioassay, daphnoretin (1), (+)-Nortrachelogenin (2), genkwanol A (3), wikstrol A (4), wikstrol B (5) and daphnodorin B (6) were isolated from the roots of Wikstroemia indica. Compounds 1-6 induced morphological deformation of P. oryzae mycelia with MMDC values of 68.4 +/- 1.3, 31.3 +/- 1.8, 45.8 +/- 0.5, 70.1 +/- 2.4, 52.3 +/- 0.9 and 73.7 +/- 1.6 microM, respectively. Compounds 3-6 showed moderate activity against microtubule polymerization with IC50 values of 112 +/- 4, 131 +/- 3, 184 +/- 6 and 142 +/- 2 microM in vitro, respectively.
    CONCLUSIONS:
    Compounds 2, 3, 5 and 6 were moderately active against HIV-1 in vitro. The findings of bioactivity of 1-6 support the antifungus, antimitosis and anti-HIV-1 uses for W. indica roots.
    Bruceoside A

    Catalog No: CFN95080
    CAS No: 63306-30-9
    Price: $318/10mg
    1,3,6-Trihydroxy-2-methylanthraquinone 3-O-alpha-L-rhamnosyl-(1->2)-beta-D-glucoside

    Catalog No: CFN95096
    CAS No: 87686-88-2
    Price: $318/10mg
    Apigenin 7-O-(6''-O-malonylglucoside)

    Catalog No: CFN95163
    CAS No: 86546-87-4
    Price: $318/5mg
    Lanceolarin

    Catalog No: CFN95166
    CAS No: 15914-68-8
    Price: $318/5mg
    (+)-Lariciresinol 4'-O-beta-D-Glucopyranosyl-(1->3)-beta-D-glucopyranoside

    Catalog No: CFN95283
    CAS No: 639857-95-7
    Price: $463/5mg
    Corymboside

    Catalog No: CFN95292
    CAS No: 73543-87-0
    Price: $318/10mg
    4,7-Didehydroneophysalin B

    Catalog No: CFN95317
    CAS No: 134461-76-0
    Price: $338/5mg
    New compound 15

    Catalog No: CFN95413
    CAS No: N/A
    Price: $413/5mg
    (R)-Mucronulatol

    Catalog No: CFN95492
    CAS No: 57128-11-7
    Price: $318/10mg
    Dihydroconfertin

    Catalog No: CFN95523
    CAS No: 68832-40-6
    Price: $318/5mg