(+)-Nortrachelogenin

(+)-Nortrachelogenin
Product Name (+)-Nortrachelogenin
CAS No.: 61521-74-2
Catalog No.: CFN96714
Molecular Formula: C20H22O7
Molecular Weight: 374.38 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Targets: HIV | Antifection
Source: The roots of Wikstroemia indica.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
(+)-Nortrachelogenin is moderately active against HIV-1 in vitro; it also can induce morphological deformation of P. oryzae mycelia with the MMDC value of 31.3 +/- 1.8 microM. (+)-Nortrachelogenin shows effects on the central nervous system producing depression in rabbits.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Antiviral Res.2021, 193:105142.
  • Food Sci Biotechnol.2023, 32(7):997-1003.
  • Agronomy2023, 13(6), 1435.
  • J Pharm Biomed Anal.2024, 247:116257.
  • EXCLI J.2023, 22:482-498.
  • Food Chem.2019, 275:746-753
  • Chinese Journal of Tissue Engineering Research2024, 28(8):1149-1154.
  • Molecules.2021, 26(6):1635.
  • Food Sci Nutr.2023, 00:1-10.
  • Phytomedicine.2024, 125:155350.
  • 2,3-Bis(3,4-dimethoxybenzyl)butyrolactone

    Catalog No: CFN98281
    CAS No: 25488-59-9
    Price: Inquiry(manager@chemfaces.com)
    Tupichilignan A

    Catalog No: CFN97182
    CAS No: 69586-96-5
    Price: Inquiry(manager@chemfaces.com)
    5-Acetoxymatairesinol dimethyl ether

    Catalog No: CFN97230
    CAS No: 74892-45-8
    Price: Inquiry(manager@chemfaces.com)
    Pluviatolide

    Catalog No: CFN92059
    CAS No: 28115-68-6
    Price: Inquiry(manager@chemfaces.com)
    Kaerophyllin

    Catalog No: CFN97234
    CAS No: 75590-33-9
    Price: Inquiry(manager@chemfaces.com)
    Meridinol

    Catalog No: CFN99313
    CAS No: 120051-54-9
    Price: Inquiry(manager@chemfaces.com)
    Savinin

    Catalog No: CFN98786
    CAS No: 493-95-8
    Price: Inquiry(manager@chemfaces.com)
    Suchilactone

    Catalog No: CFN95010
    CAS No: 50816-74-5
    Price: $338/5mg
    Isonemerosin

    Catalog No: CFN95008
    CAS No: 181524-79-8
    Price: $268/20mg
    2,3-Di(3',4'-methylenedioxybenzyl)-2-buten-4-olide

    Catalog No: CFN97895
    CAS No: 137809-97-3
    Price: Inquiry(manager@chemfaces.com)
    Lloydia. 1979 Mar-Apr;42(2):159-62.
    (+)Nortrachelogenin, a new pharmacologically active lignan from Wikstroemia indica.[Pubmed: 449625]

    METHODS AND RESULTS:
    A new lignan, (+)-Nortrachelogenin (I), and a known compound, daphnoretin were isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae).
    CONCLUSIONS:
    The structure of (+)-Nortrachelogenin was established as 8(R)8'-4,4',8'-trihydroxy-3,3'-dimethoxylignan-olid, (9,9') on the basis of spectroscopic evidence and comparison with its enantiomer, (-)-nortrachelogenin. +-nortrachelogenin(I) showed effects on the central nervous system producing depression in rabbits.
    Planta Med. 2000 Aug;66(6):564-7.
    Antifungal, antimitotic and anti-HIV-1 agents from the roots of Wikstroemia indica.[Pubmed: 10985087]

    METHODS AND RESULTS:
    With guidance of Pyricularia oryzae bioassay, daphnoretin (1), (+)-Nortrachelogenin (2), genkwanol A (3), wikstrol A (4), wikstrol B (5) and daphnodorin B (6) were isolated from the roots of Wikstroemia indica. Compounds 1-6 induced morphological deformation of P. oryzae mycelia with MMDC values of 68.4 +/- 1.3, 31.3 +/- 1.8, 45.8 +/- 0.5, 70.1 +/- 2.4, 52.3 +/- 0.9 and 73.7 +/- 1.6 microM, respectively. Compounds 3-6 showed moderate activity against microtubule polymerization with IC50 values of 112 +/- 4, 131 +/- 3, 184 +/- 6 and 142 +/- 2 microM in vitro, respectively.
    CONCLUSIONS:
    Compounds 2, 3, 5 and 6 were moderately active against HIV-1 in vitro. The findings of bioactivity of 1-6 support the antifungus, antimitosis and anti-HIV-1 uses for W. indica roots.
    Neochlorogenic acid methyl ester

    Catalog No: CFN95190
    CAS No: 123410-65-1
    Price: $198/5mg
    4,4-di(4-hydroxy-3-methoxyphenly)-2,3-dimethylbutanol

    Catalog No: CFN95200
    CAS No: 913643-31-9
    Price: $368/5mg
    N-Methylcorydalmine

    Catalog No: CFN95204
    CAS No: 81010-29-9
    Price: $398/5mg
    Trachelogenin 4'-O-beta-gentiobioside

    Catalog No: CFN95235
    CAS No: 106647-13-6
    Price: $218/10mg
    Safflospermidine A

    Catalog No: CFN95255
    CAS No: 1111082-13-3
    Price: $413/5mg
    Euphorbia factor L25

    Catalog No: CFN95339
    CAS No: 303174-98-3
    Price: $368/5mg
    New compound 14

    Catalog No: CFN95381
    CAS No: N/A
    Price: $413/5mg
    Dehydrodicatechin A

    Catalog No: CFN95451
    CAS No: 36048-23-4
    Price: $318/5mg
    beta-Hydroxyacteoside

    Catalog No: CFN95499
    CAS No: 109279-13-2
    Price: $318/10mg
    New compound 21

    Catalog No: CFN95560
    CAS No: N/A
    Price: $413/5mg