Bis-5,5-nortrachelogenin
Bis-5,5-nortrachelogenin has anti-allergic activity, it inhibited NO production with IC50 value of 48.6 microM.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Arch Biochem Biophys.2018, 644:93-99
Integr Med Res.2017, 6(4):395-403
BMC Complement Altern Med.2016, 16:213
Int J Biol Macromol.2020, 169:342-351
Legume Science2021, 3(4): e101.
Dent Mater J. 2024, dmj.2023-294.
Phytomedicine.2022, 99:153997.
Inflammation.2015, 38(4):1502-16
Environ Toxicol.2024, tox.24246
Front Pharmacol.2019, 10:1355
Related and Featured Products
Chem Pharm Bull (Tokyo). 2005 Oct;53(10):1348-51.
Lignans from the roots of Wikstroemia indica and their DPPH radical scavenging and nitric oxide inhibitory activities.[Pubmed:
16205001]
METHODS AND RESULTS:
In our investigation of in vitro anti-allergic screening of medicinal herbal extracts, the ethyl acetate extract of the root of Wikstroemia indica was observed to inhibit nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-gamma (IFN-gamma) activated murine macrophage-like cell line, RAW 264.7. Fractionation of the active extract led to the isolation of two new lignan dimer Bis-5,5-nortrachelogenin (1) and bis-5,5'-nortrachelogenin (2), and three known lignans.
CONCLUSIONS:
Compound 1 and lirioresinol B (5) inhibited NO production with IC50 values at 48.6 and 53.5 microM, respectively. Compound 5 also showed free radical scavenging effect on 1,1-diphenyl-2-picrylhydrazil (DPPH) at IC50 values at 19.5 microM.
3,3',4',5,6,7,8-heptamethoxyflavone
Catalog No: CFN95021
CAS No: 1178-24-1
Price: $268/10mg
5,7,2',4'-Tetrahydroxy-8,3'-di(gamma,gamma-dimethylallyl)-isoflavanone
Catalog No: CFN95084
CAS No: 141846-47-1
Price: $413/5mg
(3E,5E,11E)-tridecatriene-7,9-diyne-1,2-diacetate
Catalog No: CFN95191
CAS No: 94753-06-7
Price: $318/5mg
Corymboside
Catalog No: CFN95292
CAS No: 73543-87-0
Price: $318/10mg
Diosmin Impurity 8
Catalog No: CFN95309
CAS No: 28719-21-3
Price: $318/10mg
Diosniposide B
Catalog No: CFN95333
CAS No: N/A
Price: $413/5mg
Protocatechuic acid 4-O-beta-glucoside
Catalog No: CFN95557
CAS No: 7361-59-3
Price: $413/5mg
Oxyphyllol B
Catalog No: CFN95575
CAS No: 226546-99-2
Price: Inquiry(manager@chemfaces.com)
Mahuannin E
Catalog No: CFN95585
CAS No: 1173887-70-1
Price: $318/5mg
4-Keto-laurifoline
Catalog No: CFN95594
CAS No: N/A
Price: $318/10mg
