Bis-5,5-nortrachelogenin
Bis-5,5-nortrachelogenin has anti-allergic activity, it inhibited NO production with IC50 value of 48.6 microM.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Phytomedicine.2021, 2(82):153452
J Pharmaceut Biomed2020, 182:113110
J Chromatogr B Analyt Technol Biomed Life Sci.2021, 1187:123012.
Phytochemistry2018, 15:83-92
Korean J. Food Sci. & Technol.2022, 54(2):241-246
Aging (Albany NY).2021, 13(19):22867-22882.
Front Nutr.2023, 10:1181135.
VNU Journal of Science: Med.& Pharm. Sci.2022, 38(2):2588-1132.
Pharmacol Rep.2019, 71(2):289-298
Int J Mol Sci.2022, 23(5):2796.
Related and Featured Products
Chem Pharm Bull (Tokyo). 2005 Oct;53(10):1348-51.
Lignans from the roots of Wikstroemia indica and their DPPH radical scavenging and nitric oxide inhibitory activities.[Pubmed:
16205001]
METHODS AND RESULTS:
In our investigation of in vitro anti-allergic screening of medicinal herbal extracts, the ethyl acetate extract of the root of Wikstroemia indica was observed to inhibit nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-gamma (IFN-gamma) activated murine macrophage-like cell line, RAW 264.7. Fractionation of the active extract led to the isolation of two new lignan dimer Bis-5,5-nortrachelogenin (1) and bis-5,5'-nortrachelogenin (2), and three known lignans.
CONCLUSIONS:
Compound 1 and lirioresinol B (5) inhibited NO production with IC50 values at 48.6 and 53.5 microM, respectively. Compound 5 also showed free radical scavenging effect on 1,1-diphenyl-2-picrylhydrazil (DPPH) at IC50 values at 19.5 microM.
Tessaric acid
Catalog No: CFN95182
CAS No: 58142-10-2
Price: $318/5mg
Neochlorogenic acid methyl ester
Catalog No: CFN95190
CAS No: 123410-65-1
Price: $198/5mg
Cichoriin
Catalog No: CFN95196
CAS No: 531-58-8
Price: $100/20mg
4'-Hydroxy-5,7,3'-trimethoxyflavone
Catalog No: CFN95398
CAS No: 1239-68-5
Price: $318/5mg
2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene
Catalog No: CFN95428
CAS No: 1608462-12-9
Price: $318/10mg
Neoorthosiphol A
Catalog No: CFN95447
CAS No: 243448-72-8
Price: $318/10mg
Gardoside methyl ester
Catalog No: CFN95467
CAS No: 93930-20-2
Price: $318/10mg
12beta-Acetoxy-3beta-hydroxy-7,11,15,23-tetraoxo-lanost-8,20-diene-26-oic acid
Catalog No: CFN95468
CAS No: 1085338-75-5
Price: $318/5mg
6-Methoxyfraxinellone
Catalog No: CFN95485
CAS No: N/A
Price: $318/10mg
Ganoderenic acid G
Catalog No: CFN95517
CAS No: 120481-73-4
Price: $318/5mg
