Moslosooflavone

Moslosooflavone
Product Name Moslosooflavone
CAS No.: 3570-62-5
Catalog No.: CFN98475
Molecular Formula: C17H14O5
Molecular Weight: 298.3 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Yellow powder
Targets: NF-kB | IFN-γ | IL Receptor | NO | TNF-α
Source: The herbs of Mosla soochouensis Matsuda
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $168/20mg
Moslosooflavone has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice. Moslosooflavone significantly inhibits the transcriptional activity of NF-kappaB in LPS/IFN-gamma stimulated RAW 264.7 macrophages.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Appl. Sci.2020, 10(8),2804
  • Nat Prod Commun.2018, 10.1177
  • Front Cell Dev Biol.2021, 9:764263.
  • Antioxidants (Basel).2024, 13(3):340.
  • Front Mol Neurosci.2023, 15:1083189.
  • Phytomedicine.2022, 96:153877.
  • Pharmacol Rep.2018, 70(6):1195-1201
  • Biomed Pharmacother.2021, 137:111362.
  • J of the Korean Society of Cosmetics and Cosmetology2019, 225-231
  • Plants (Basel).2021, 10(7):1376.
  • Oroxylin A

    Catalog No: CFN98540
    CAS No: 480-11-5
    Price: $80/20mg
    Negletein

    Catalog No: CFN91886
    CAS No: 29550-13-8
    Price: Inquiry(manager@chemfaces.com)
    Mosloflavone

    Catalog No: CFN90893
    CAS No: 740-33-0
    Price: $188/20mg
    6-Hydroxywogonin

    Catalog No: CFN95009
    CAS No: 76844-70-7
    Price: $368/5mg
    6-Methoxywogonin

    Catalog No: CFN98403
    CAS No: 3162-45-6
    Price: $318/5mg
    6-Methoxyflavone

    Catalog No: CFN70090
    CAS No: 26964-24-9
    Price: $30/20mg
    6,7-Dihydroxyflavone

    Catalog No: CFN70351
    CAS No: 38183-04-9
    Price: $118/20mg
    3,6-Dihydroxyflavone

    Catalog No: CFN70020
    CAS No: 108238-41-1
    Price: $70/20mg
    7,8-Dihydroxyflavone

    Catalog No: CFN96512
    CAS No: 38183-03-8
    Price: $50/20mg
    Chrysin

    Catalog No: CFN98741
    CAS No: 480-40-0
    Price: $40/20mg
    J Agric Food Chem. 2010 Feb 24;58(4):2505-12.
    Anti-inflammatory activity of new compounds from Andrographis paniculata by NF-kappaB transactivation inhibition.[Pubmed: 20085279]
    Previous studies showed that the ethyl acetate (EtOAc) fraction of Andrographis paniculata (AP) possessed anti-inflammatory activity. This study further isolated these active compounds from bioactivity-guided chromatographic fractionation and identified eight pure compounds.
    METHODS AND RESULTS:
    Reporter gene assay indicated that 5-hydroxy-7,8-dimethoxyflavone (1), Moslosooflavone (2), a mix of beta-sitosterol (3a) and stigmasterol (3b), ergosterol peroxide (4), 14-deoxy-14,15-dehydroandrographolide (5), and a new compound, 19-O-acetyl-14-deoxy-11,12-didehydroandrographolide (6a), significantly inhibited the transcriptional activity of NF-kappaB in LPS/IFN-gamma stimulated RAW 264.7 macrophages (P < 0.05). The two most abundant compounds, 14-deoxy-11,12-didehydroandrographolide (7) and andrographolide (8), had less inhibitory activity but exerted greater inhibitory activity by hydrogenation, oxidation, or acetylation to become four derived compounds, 9, 10, 11, and 12. All of the compounds significantly decreased TNF-alpha, IL-6, macrophage inflammatory protein-2 (MIP-2), and nitric oxide (NO) secretions from LPS/IFN-gamma stimulated RAW 264.7 cells. Compounds 5, 11, and 12 exerted the strongest inhibitory effect on NF-kappaB-dependent transactivation in the RAW 264.7 cell, with IC(50) values of 2, 2.2, and 2.4 microg/mL, respectively, providing encouraging results for bioactive compound development.
    Zhong Yao Cai. 2015 Jan;38(1):89-92.
    Chemical Constituents with Anti-hypoxia Activity from Saussurea involucrata.[Pubmed: 26214875]
    To investigate the chemical constituents with anti-hypoxia activity from Saussurea involucrata.
    METHODS AND RESULTS:
    The chemical constituents, isolated and purified by column chromatography from Saussurea involucrata, were identified by several spectroscopic methods. The anti-hypoxic activities of these compounds were examined using the normobaric hypoxic model of mice. Twelve compounds were isolated from petroleum ether extract of Saussurea involucrata and identified as n-octacosane (1), 1-undecanol (2), heptadecan-l-ol(3), heptacosan-1-ol(4), myristicin (5), apiol(6), β-sitosterol(7), lupeol(8), Moslosooflavone (9), mosloflavone (10), negletein(11), and 5, 6-dihydroxy-7, 8-dimethoxyflavone(12).
    CONCLUSIONS:
    All compounds except 7 and 8 are isolated from this plant for the first time. Compound 1, 5 and 8 - 12 can significantly prolong the survival time of hypoxic mice.
    Nat Prod Commun. 2015 Mar;10(3):387-8.
    Convergent synthesis of moslosooflavone, isowogonin and norwogonin from chrysin.[Pubmed: 25924511]
    A convergent synthesis route of Moslosooflavone, isowogonin and norwogoninis reported,starting from chrysin, an easily available flavone, by methylation, bromination, methoxylation and demethylation procedures. This synthetic route is convenient and can give the three rare flavones in good yield.
    Carasiphenol C

    Catalog No: CFN95045
    CAS No: 868168-04-1
    Price: $368/5mg
    Yuankanin

    Catalog No: CFN95128
    CAS No: 77099-20-8
    Price: $318/5mg
    Lanceolarin

    Catalog No: CFN95166
    CAS No: 15914-68-8
    Price: $318/5mg
    Tessaric acid

    Catalog No: CFN95182
    CAS No: 58142-10-2
    Price: $318/5mg
    Ginsenoside Rd2 (Quinquenoside L10)

    Catalog No: CFN95231
    CAS No: 83480-64-2
    Price: $318/10mg
    Daucoidin A

    Catalog No: CFN95275
    CAS No: 103629-87-4
    Price: $318/5mg
    Theaflavanoside II

    Catalog No: CFN95380
    CAS No: 943785-09-9
    Price: $318/5mg
    Cannabisin M

    Catalog No: CFN95436
    CAS No: 1831134-13-4
    Price: $318/5mg
    Quercetin 3,5-O-diglucoside

    Catalog No: CFN95486
    CAS No: 206257-35-4
    Price: $368/10mg
    Oxytroflavoside B

    Catalog No: CFN95490
    CAS No: 1391144-81-2
    Price: $318/10mg