Isorhynchophyllic acid | CAS:144525-05-3

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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Two new ortho benzoquinones from Uncaria rhynchophylla.[Pubmed: 27025371]

The present study was designed to determine the chemical constituents of the stems and hooks of Uncaria rhynchophylla.
METHODS AND RESULTS:
The chemical constituents were isolated and purified from CH2Cl2 fraction by chromatography. Their structures were elucidated by spectroscopic analyses. Their cytotoxicity was tested using MTT method. Two new ortho benzoquinones, 3-diethylamino-5-methoxy-1, 2-benzoquinone (1) and 3-ethylamino-5-methoxy-1, 2-benzoquinone (2), together with a known compound Isorhynchophyllic acid (3) were isolated from U. rhynchophylla. These compounds were evaluated for their cytotoxicity against cancer cells A549, HepG2 and A2780.
CONCLUSIONS:
Compounds 1 and 2 were new ortho benzoquinones and showed weak antiproliferative activities on A549, HepG2 and A2780 cells. Compound 3 significantly inhibited the proliferation of A549, HepG2 and A2780 cells with IC50 values being 5.8, 12.8 and 11.8 μmol·L(-1), respectively.

Product Name	Isorhynchophyllic acid
CAS No.:	144525-05-3
Catalog No.:	CFN98132
Molecular Formula:	C₂₁H₂₆N₂O₄
Molecular Weight:	370.44 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	White cryst.
Source:	The herbs of Uncaria rhynchophylla.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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