Isomaculosidine

Isomaculosidine
Product Name Isomaculosidine
CAS No.: 518-96-7
Catalog No.: CFN96765
Molecular Formula: C14H13NO4
Molecular Weight: 259.26 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Targets: NO
Source: The root barks of Dictamnus dasycarpus.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Isomaculosidine can significantly inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 cells.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Processes2021, 9(1), 153.
  • Environ Toxicol.2020, doi: 10.1002
  • J of Essential Oil Research2019, 1677272
  • ACS Pharmacol. Transl. Sci.2023, 3c00129.
  • PLoS One.2015, 10(5):e0127060
  • Russian J Bioorganic Chemistry 2021, 47:1411-1417.
  • Industrial Crops and Products2020, 146:112186
  • PLoS One.2021, 16(6):e0248479.
  • Evid Based Complement Alternat Med.2017, 2017:7383104
  • Cells.2023, 12(3):395.
  • Isodictamnine

    Catalog No: CFN96762
    CAS No: 484-74-2
    Price: Inquiry(manager@chemfaces.com)
    Isopteleine

    Catalog No: CFN96763
    CAS No: 2181-84-2
    Price: Inquiry(manager@chemfaces.com)
    Isomaculosidine

    Catalog No: CFN96765
    CAS No: 518-96-7
    Price: Inquiry(manager@chemfaces.com)
    Robustine

    Catalog No: CFN96362
    CAS No: 2255-50-7
    Price: $368/10mg
    gamma-Fagarine

    Catalog No: CFN98858
    CAS No: 524-15-2
    Price: $288/5mg
    Maculosidin

    Catalog No: CFN95126
    CAS No: 522-19-0
    Price: $413/5mg
    Haplopine

    Catalog No: CFN96010
    CAS No: 5876-17-5
    Price: $318/5mg
    Skimmianin

    Catalog No: CFN92555
    CAS No: 83-95-4
    Price: $288/20mg
    7-Isopentenyloxy-gamma-fagarine

    Catalog No: CFN98242
    CAS No: 23417-92-7
    Price: Inquiry(manager@chemfaces.com)
    Evodine

    Catalog No: CFN90488
    CAS No: 6989-38-4
    Price: $413/5mg
    J Enzyme Inhib Med Chem. 2012 Aug;27(4):490-4.
    Inhibitory alkaloids from Dictamnus dasycarpus root barks on lipopolysaccharide-induced nitric oxide production in BV2 cells.[Pubmed: 21827366 ]

    METHODS AND RESULTS:
    The methanolic extract of Dictamnus dasycarpus root barks afforded one new glycosidic quinoline alkaloid, 3-[1β-hydroxy-2-(β-D-glucopyranosyloxy)-ethyl)-4-methoxy-2(1H)-quinolinone (1), together with nine known compounds, preskimmianine (2), 8-methoxy-N-methylflindersine (3), dictamine (4), γ-fagarine (5), halopine (6), skimmianine (7), dictangustine-A (8), iso-γ-fagarine (9), Isomaculosidine (10).
    CONCLUSIONS:
    The isolated alkaloids significantly inhibited nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 cells. Among them, compounds 3 and 7 showed the most potent inhibitory activities on LPS-induced NO production.
    3,3',4',5,6,7,8-heptamethoxyflavone

    Catalog No: CFN95021
    CAS No: 1178-24-1
    Price: $268/10mg
    Gymnoside III

    Catalog No: CFN95033
    CAS No: 899430-03-6
    Price: $238/10mg
    2''-O-Galloylquercitrin

    Catalog No: CFN95041
    CAS No: 80229-08-9
    Price: $418/5mg
    Spinacetin

    Catalog No: CFN95194
    CAS No: 3153-83-1
    Price: $318/5mg
    Quercetin-3'-glucoside

    Catalog No: CFN95271
    CAS No: 19254-30-9
    Price: $318/10mg
    alpha-Costic acid

    Catalog No: CFN95322
    CAS No: 28399-17-9
    Price: $318/5mg
    5,6,7,3',4',5'-Hexamethoxyflavanone

    Catalog No: CFN95376
    CAS No: 74064-17-8
    Price: $318/10mg
    10-O-trans-p-coumaroylscandoside

    Catalog No: CFN95391
    CAS No: 870785-25-4
    Price: $318/10mg
    Malabaricone A

    Catalog No: CFN95477
    CAS No: 63335-23-9
    Price: $318/10mg
    8-Epiloganin

    Catalog No: CFN95478
    CAS No: 79172-04-6
    Price: $318/20mg