Isodonal
Isodonal shows abilities to inhibit K562 cells camparable to that of cisplatin.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Molecules.2020, 25(20):4851.
J of Pharmaceutical Analysis2020, doi: 10.1016
BMC Complement Altern Med.2019, 19(1):339
J Biomol Struct Dyn.2022, 5;1-17.
Curr Med Sci.2024, 44(2):355-368.
Arch Biochem Biophys.2020, 687:108384.
Pharmaceuticals (Basel).2020, 13(10):302.
J Biotechnol.2020, 318:10-19.
J Drug Target.2016, 24:1-28
Br J Pharmacol.2016, 173(2):396-410
Related and Featured Products
Chin J Nat Med. 2012 Jan;10(1):43-7.
Chemical constituents of flowers and fruits of Rabdosia excisa.[Pubmed:
23302530]
To study the chemical constituents in the flowers and fruits of Rabdosia excisa.
METHODS AND RESULTS:
The compounds were isolated and purified by silica gel column chromatography and their structures were identified by spectroscopic methods.
Sixteen compounds isolated from the flowers and fruits of this plant were identified as: stigm asterol (I), α-amyrin palmitate (II), ursolic acid (III), 2α, 3α, 19-trihydroxy-urs-12-en-28-oic acid (IV), 2α-hydroxyursolic acid (V), maslinic acid (VI), Isodonal (VII), maoyecrystal E (VIII), kamebakaurin (XI), macrocalyxin G (X), epinodosinol (XI), rabdosichuanin C (XII), kamebacetal A (XIII), oridonin (XIV), enmenol-glucoside (XV), and lasiononin (XVI).
CONCLUSIONS:
All the constituents were found in Rabdosia excisa for the first time, except constituents III, IX, XII and XIV.
Chemical & Pharmaceutical Bulletin,2003, 51(7):790-3.
Ent-kaurane diterpenoids from Isodon rubescens var. lushanensis.[Reference:
WebLink]
METHODS AND RESULTS:
Four new ent-kaurane diterpenoids lushanrubescensins F—I (1—4), together with 11 known ones, lasiodonin (5), oridonin (6), ponicidin (7), isodonoiol (8), Isodonal (9), rabdosin B (10), rabdoternins A and B (11
and 12), enmenol (13), epinodosin (14), and inflexusin (15), were isolated from Isodon rubescens var. lushanensis,
and the structures were elucidated by spectroscopic analysis. The inhibitory effect against the K562, Bcap37,
BGC823, BIU87, CA, CNE, and Hela cell lines of compounds 3 and 5—10 were evaluated.
