(-)-Haplomyrfolin
(-)-Haplomyrfolin is a natural product from Platycladus orientalis.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Phytother Res.2022, 10.1002:ptr.7626.
Antioxidants (Basel).2023, 13(1):12.
Int J Mol Sci.2019, 20(8):E1855
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Pharmacol Rep.2020, 72(2):472-480.
J Nat Med.2022, 76(1):59-67.
Biomedicines.2024, 12(3):495.
LWT2024, 200:116184.
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Phytochemistry, 1996 , 42 (3) :695-699.
Lignans, alkaloids and coumarins from Haplophyllum vulcanicum ☆[Reference:
WebLink]
METHODS AND RESULTS:
Six lignans, (-)-haplomyrfolol, (-)-Haplomyrfolin, (-)-kusunokinin, (-)-syringaresinol, diphyllin and (-)-tuberculatin, five furoquinoline alkaloids, dictamnine, gamma-fagarine, haplopine, robustine and skimmianine, and two coumarins, scopoletin and umbelliferone, have been isolated from Haplophyllum vulcanicum. (-)-Haplomyrfolol, a novel dibenzylbutyrolactol, exists as an epimeric mixture in solution. Complete assignments of the proton and carbon chemical shifts for the individual epimers were accomplished on the basis of high resolution 1D and 2D NMR data.
CONCLUSIONS:
This is the first report of (-)-syringaresinol from the genus Haplophyllum and of (-)-Haplomyrfolin, (-)-tuberculatin, dictamnine, haplopine and umbelliferone from the title species.
