Gnetumontanin B
Gnetumontanin B shows potent inhibition of TNF-alpha.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Int J Mol Sci.2021, 22(9):5012.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess.2020, 37(9):1437-1448.
Nat Prod Sci.2019, 25(3):238
Korean J. Medicinal Crop Sci.2023, 31(6):388-395.
Food Funct.2024, 15(8):4262-4275.
International Food Research Journal2018, 25(6):2560-2571
J Exp Bot.2016, 67(12):3777-88
Nutrients.2021, 13(3):978.
Mol Biol Rep.2022, doi: 10.1007
BMC Plant Biol.2021, 21(1):60.
Related and Featured Products
Planta Med. 2004 Feb;70(2):160-5.
Four new stilbenoids from the lianas of Gnetum montanum f. megalocarpum.[Pubmed:
14994195]
METHODS AND RESULTS:
From the lianas of Gnetum montanum Markgr. f. megalocarpum Markgr., four new stilbenoids, gnetumontanins A - D ( 1 - 4) were obtained together with 16 known compounds. Gnetumontanin A ( 1) is the first oligostilbene dimerized from two oxyresveratrol units, Gnetumontanin B ( 2) is a new stilbene trimer oligomerized from two oxyresveratrol and one resveratrol units, gnetumontanin C ( 3) is a new stilbenoid with a novel skeleton having a delta-lactone moiety and gnetumontanin D ( 4) is a glucoside of 3. Their structures were determined by means of spectroscopic evidence, especially 2D NMR techniques.
CONCLUSIONS:
Gnetumontanin B showed potent inhibition of TNF-alpha with an inhibitory ratio of 58.1 % (P < 0.05) at a concentration of 10 ( - 5) mol L (-1) and the IC (50) was 1.49 x 10 ( - 6) mol L (-1).
