Ginsenoside Rk2
Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation
activities. Ginsenoside Rk1 can strongly inhibit permeability induced by VEGF, advance glycation end-product, thrombin, or histamine in human retinal endothelial cells, it reduces the vessel leakiness of retina in a diabetic mouse model; this anti-permeability activity of Rk1 is correlated with enhanced stability and positioning of tight junction proteins at the boundary between cells; Rk1 induces phosphorylation of myosin light chain and cortactin, which are critical regulators for the formation of the cortical actin ring structure and endothelial barrier.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Molecules.2024, 29(3):671.
J Ginseng Res.2020, 44(4):611-618.
Int J Mol Sci.2021, 22(19):10220.
Int J Mol Sci.2019, 20(9):E2244
Mediators Inflamm.2016, 2016:7216912
Int J Mol Sci.2021, 22(8):4211.
In Vitro Cellular & Developmental Biology - Plant2022, 58:972-988.
Comp. & Mathematical Methods in Med.2022, 5475559.
Cancers (Basel).2023, 15(1):37.
J Cell Biochem.2022, 123(7):1222-1236.
Related and Featured Products
Arch Pharm Res. 2002 Aug;25(4):428-32.
Three new dammarane glycosides from heat processed ginseng.[Pubmed:
12214849]
Three new dammarane glycosides were isolated from the processed ginseng (SG; Sun Ginseng).
METHODS AND RESULTS:
Their structure were determined to be 3beta,12beta-dihydroxydammar-20(21),24-diene-3-O-beta-D-glucopyranosyl(1 --> 2)-beta-D-glucopyranoside; 3beta,12beta-dihydroxydammar-20(21),24-diene-3-O-beta-D- glucopyranoside and 3beta,6alpha,12beta-trihydroxydammar-20(21),24-diene-6-O-beta-D-glucopyranoside based on spectroscopic evidences.
CONCLUSIONS:
The compounds were named as Ginsenoside Rk1, Ginsenoside Rk2, and ginsenoside Rk3 respectively.
