Flavaprin
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Fitoterapia.2024, 177:106138.
Int J Mol Sci.2024, 25(17):9730.
The University of Manitoba2021, 35690.
Separations2023, 10(7), 411.
Biomed Pharmacother.2020, 128:110318.
Curr Issues Mol Biol.2024, 46(4):3328-3341.
JEJU National University2022, 24032.
J Med Chem.2023, 66(6):4106-4130.
Korean J of Crop Science2019, 452-458
National University of Pharmacy2022, 1:73-76
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Arch Pharm Res. 2002 Dec;25(6):824-30.
Constituents of the fruits and leaves of Euodia daniellii.[Pubmed:
12510833]
METHODS AND RESULTS:
Four flavonoid glycosides, Flavaprin (7), evodioside B (8), vitexin (11), and hesperidin (12), as well as the coumarins bergapten (1), xanthotoxin (2), and isopimpinellin (3), the lignan simplexoside (10), the steroids beta-sitosterol (4) and daucosterol (5), the limonoids isolimonexic acid (6) and limonin (9), and uracil (13) and myo-inositol (14) have been isolated from Euodia daniellii. The structures of these compounds were established from spectral data.
CONCLUSIONS:
Among the isolates, bergapten showed cyclooxygenase-2 inhibitory activity with an IC50 value of 6.2 microg/ml. Flavonoids isolated from this plant exhibited no cytotoxic activity against the human tumor cell lines, A549, SKOV-3, SKMEL-2, XF498, and HCT15.
