Dibritannilactone B
Dibritannilactone B is a natural product from Inula britannica.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Toxicol In Vitro.2019, 59:161-178
PLoS One.2022, 17(6):e0268505.
Food Chem Toxicol.2024, 186:114589.
J Food Composition and Analysis2022, 104417.
Microbiol. Biotechnol. Lett.2022, 50(2): 193-201.
Int J Mol Sci.2020, 21(19),7070.
Biomed Sci Letters.2020, 26:319-326
Front Pharmacol.2022, 13:806869.
Pharmacognosy Journal.2020, 12(2), p232-235.
Int Immunopharmacol.2019, 71:22-31
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Rsc Advances, 2015, 46(22):1979-1982.
One new unusual sesterterpenoid and four new sesquiterpene dimers from Inula britannica.[Reference:
WebLink]
METHODS AND RESULTS:
One new unusual sesterterpenoid (Dibritannilactone A,1), four new sesquiterpene dimers (Dibritannilactone B, Dibritannilactone C, Dibritannilactone D, Dibritannilactone E,2–5) together with nine known sesquiterpenes (6–14) were isolated from the aerial parts of Inula britannica.
CONCLUSIONS:
The structures of the new compounds were elucidated by detailed spectroscopic analysis, including HR-ESIMS and 2D-NMR spectroscopic methods. In addition, compounds 1–8 and 10–11 were tested for their inhibitory effects against LPS-induced NO production in RAW264.7 macrophages.
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