Cyclo(L-Leu-trans-4-hydroxy-L-Pro)
Cyclo(L-Leu-trans-4-hydroxy-L-Pro) is a natural product from Phellinus igniarius.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Phytomedicine.2023, 120:155063.
Applied Biological Chemistry2022, 65(12)
SRM Institute of Sci&Tech2022, 34(1): 32-37
iScience.2024, 27(8):110496.
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JPC-Journal of Planar Chromatography 2017, 30(4)
JPC-Journal of Planar Chromatography 2017, 30(2)
J Nat Med.2021, doi: 10.1007.
Biomolecules.2024, 14(4):451.
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Chemical Research & Application, 2014 (9) :1478-1482.
Cyclic dipeptides metabolites from the symbiotic fungus paraconiothyrium brasiliense[Reference:
WebLink]
Nine cyclic dipeptides secondary metabolites were isolated from the symbiotic fungus paraconiothyrium brasiliense,by normal phase silica gel,Sephadex LH-20 chromatography and reverse phase HPLC.
METHODS AND RESULTS:
Their structures were elucidated as cyclo-( LLeu-L-Tyr)(1),cyclo-(L-Trp-L-Pro)(2),cyclo-( L-Pro-L-Phe)(3),cyclo-( L-Pro-L-Tyr)(4),cyclo-( L-Pro-L-Leu)(5),Cyclo(L-Leu-trans-4-hydroxy-L-Pro)(6),cyclo-(L-Ile-L-Pro)(7),cyclo-(L-Val-L-Pro)(8),cyclo-(L-Leu-L-Ile)(9)by NMR,MS and physicochemical properties.
CONCLUSIONS:
All the compounds were isolated from the symbiotic fungus paraconiothyrium brasiliense for the first time.
