Cyclo(D-Leu-L-Pro)
Cyclo(D-Leu-L-Pro) shows antitumour and antifungal activities.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Biofactors.2018, 44(2):168-179
Jeju National University Graduate School2023, 24478
Mol Microbiol.2019, 112(1):317-332
Nature Ecology & Evolution2020, doi: 10.1038
Sci Rep.2023, 13(1):13610.
The University of Manitoba2021, 35690.
Evid Based Complement Alternat Med.2021, 2021:8847358.
Natural Product Communications2020, doi: 10.1177.
Evid Based Complement Alternat Med.2016, 2016:4357656
Neurotoxicology.2022, 91:218-227.
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Natural Product Research and Development,2007,19(5):956.
Metabolites of endophytic fungus GT20036029 isolated from the mangrove plant Hibiscus tiliaceus.[Reference:
WebLink]
Nine compounds were isolated from the culture broth of a mangrove endophytic fungus GT20036029,which was isolated from a semi-mangrove plant Hibiscus tiliaceus.
METHODS AND RESULTS:
They were identified as N-(2-hydroxyphenethyl)acetamide(1),cyclo(L-Pro-D-Ile)(2),cyclo(L-Leu-L-Pro)(3),Cyclo(D-Leu-L-Pro)(4),cyclo(Leu-Tyr)(5),cyclo(Phe-Ser)(6),cerebroside B(7),(25S)-nuatigenin-3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside(8) and(25S)-isonuati-genin-3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyanoside(9) on the basis of spectroscopic data analyses.
METHODS AND RESULTS:
Compound 1 was firstly isolated from marine fungus,while compound 8 showed significant growth inhibition of tumor cells.
