Cyclo(Pro-Leu)
Cyclo(Pro-Leu) has brine shrimp lethality.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Phytother Res.2020, 34(4):788-795.
Current Analytical Chemistry2024, 20(8):599-610.
Nature Ecology & Evolution2020, doi: 10.1038
Molecules.2024, 29(21):5161.
Molecular & Cellular Toxicology2022, 10.1007:s13273-022-00277-3
bioRxiv-Pharm.&Toxi.2022, 2022.481203.
Materials Today Communications2023, 37:107216
World J Mens Health.2019, 10.5534
Appl. Sci. 2021, 11(22), 10552
Pharmaceuticals (Basel).2024, 17(9):1130.
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Nat Prod Res. 2014;28(7):473-6.
A new diketopiperazine from the gorgonian coral Menella kanisa.[Pubmed:
24479814]
Chemical investigation on the gorgonian Menella kanisa collected from Beibu Gulf led to the isolation of a new diketopiperazine, named menazepine A (1), as well as three known diketopiperazines, namely cyclo(4-hydroxyprolylleucyl) (2), Cyclo(Pro-Leu) (3) and cyclo(4-hydroxyprolylphenylalanyl) (4).
METHODS AND RESULTS:
The structure of the new diketopiperazine was elucidated on the basis of extensive spectroscopic analysis and by comparing the data with those of related metabolites. Compounds 1-4 were also evaluated for brine shrimp lethality.
