Cimicifugoside H2
Cimicifugoside H2 is a natural product from Cimicifuga foetida.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
J. of The Korean Society of Food Culture2017, 144-149
Mol Biol Rep.2023, 50(5):4029-4038.
Korean Journal of Plant Resources2021, 34(1):52-58.
Molecules.2023, 28(13):4971.
Asian J of Pharmaceutical&Clinical 2018, 11(2)
Research SPJ.2024, 0377.
J Agric Food Chem.2024, acs.jafc.4c01387.
J Biochem Mol Toxicol.2022, e23211.
Separations2021, 8(7),90.
J AOAC Int.2021, 104(6):1634-1651.
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Zhongguo Zhong Yao Za Zhi. 2009 Aug;34(15):1930-4.
Cycloartane triterpenoid of Cimicifuga foetida.[Pubmed:
19894537]
To study cycloartane triterpenoid of Cimicifuga foetida and their osteoclast inhibition activity.
METHODS AND RESULTS:
The compounds were isolated and purified by normal and reversed phase column chromatographic methods. Structures were identified by spectroscopic analyses. Their osteoclast inhibition activity was then studied.Thirteen cycloartane triterpenoids were isolated from the rhizomes of C. foetida and were characterized as 25-O-acetyl-cimigenol (1), cimigenol (2), cimicidanol (3), 26-deoxyactein (4), asiaticoside A (5), 23-epi-26-deoxyactein (6), actein (7), 12beta-hydroxycimigenol (8), cimiside E (9), (23R, 24S) 25-O-acetyl-cimigenol-3-O-beta-D-xylopyranoside (10), (23R, 24S) cimigenol-3-O-beta-D-xylopyranoside (11), cimicifugoside H1 (12) and Cimicifugoside H2 (13).
CONCLUSIONS:
Compound 5 was isolated from this genus for the first time, compound 7 was isolated firstly from the plant and compound 2, 7, 10 and 11 exhibit osteoclast inhibition activity.
