Chloramultilide D
Chloramultilide D is a natural product from Chloranthus spicatus.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Natural Product Communications2020, doi: 10.1177.
Toxicol In Vitro.2023, 86:105521.
J Pharm Biomed Anal.2019, 172:268-277
Front Pharmacol.2021, 12:652860.
Plant Cell, Tissue and Organ Culture (PCTOC)2024, 158:54
Srinagarind Medical Journal2019, 34(1)
Mol Med Rep.2022, 26(4):299.
Planta Med.2019, 85(9-10):766-773
Drug Dev Res.2022, 83(7):1673-1682.
Front Endocrinol (Lausanne).2020, 11:568436.
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J Nat Prod. 2007 Dec;70(12):1987-90
Mono- and Di-sesquiterpenoids from Chloranthus spicatus.[Pubmed:
18044839 ]
METHODS AND RESULTS:
Three new dimeric sesquiterpenoids, chloramultilide B, chloramultilide C, Chloramultilide D ( 1- 3), along with 10 known sesquiterpenoids, were isolated from the whole plant of Chloranthus spicatus. Their structures were established by physical data (1D and 2D NMR, MS).
CONCLUSIONS:
The structure and absolute configuration of 1 was confirmed by X-ray crystallography. Compound 1 exhibited moderate in vitro antifungal activity.
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