Caulophyllumine A
Caulophyllumine A is a natural product from Cimicifuga heracleifolia.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
J Pharm Biomed Anal.2024, 241:115990.
US20170000760 A12016, 42740
Drug Des Devel Ther.2020, 14:61-71
Separations2021, 8(6),80.
Cell Physiol Biochem.2017, 44(4):1381-1395
Appl. Sci.2023, 13(2), 860.
J Sep Sci.2018, 41(9):1938-1946
ACS Pharmacol Transl Sci.2024, 7(2):395-405.
Clin Exp Pharmacol Physiol.2015, 42(11):1189-97
Mol Neurobiol.2023, 60(12):7196-7207.
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Phytochemistry. 2008 Feb;69(4):1037-42.
Alkaloids and saponins from blue cohosh.[Pubmed:
18048069 ]
Blue cohosh, Caulophyllum thalictroides (L.) Michx. (Berberidaceae), is used primarily to cure menstrual disturbances and to ease childbirth. Alkaloids and saponins are considered to be responsible for its pharmacological activity.
METHODS AND RESULTS:
A detailed phytochemical investigation of blue cohosh resulted in the isolation of 15 compounds belonging to the alkaloids and the triterpene saponins.
CONCLUSIONS:
The structures of two alkaloids, Caulophyllumine A (1) and caulophyllumine B (2) and a saponin, cauloside H (3) both previously unknown were determined by spectroscopic techniques, including by 1- and 2-D NMR as well as by chemical analysis.
