Broussonin B

Broussonin B
Product Name Broussonin B
CAS No.: 73731-86-9
Catalog No.: CFN97695
Molecular Formula: C16H18O3
Molecular Weight: 258.32 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The branches of Broussonetia papyrifera.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $318/10 mg
Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin B can induce neurite outgrowth in PC-12 cells at concentration of 50 microg/ml, and show moderate inhibitory activities against a chymotrypsin-like activity of the proteasome.Broussonin B also can significantly inhibit adipocyte differentiation in 3T3-L1 cells as measured fat accumulation using Oil Red O assay.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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  • J Drug Target.2016, 24:1-28
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  • The Pharmaceutical Society of Japan2018, 138(4):571-579
  • Int J Cosmet Sci.2019, 41(1):12-20
  • New Journal of Chemistry2019, 43:12538-12547
  • The Korea Journal of Herbology2019, 34(2):25-32
  • Comput Biol Chem.2019, 83:107096
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    Biol Pharm Bull. 2005 Sep;28(9):1798-800.
    7-hydroxy-3-(4-hydroxybenzyl)chroman and broussonin b: neurotrophic compounds, isolated from Anemarrhena asphodeloides BUNGE, function as proteasome inhibitors.[Pubmed: 16141565 ]

    METHODS AND RESULTS:
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    These phytoalexins are characterized structurally by a 1,3-diphenylpropane skeleton.
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