Broussonin B
Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin B can induce neurite outgrowth in PC-12 cells at concentration of 50 microg/ml, and show moderate inhibitory activities against a chymotrypsin-like activity of the proteasome.Broussonin B also can significantly inhibit adipocyte differentiation in 3T3-L1 cells as measured fat accumulation using Oil Red O assay.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Asian J Beauty Cosmetol2020, 18(3): 265-272.
Phytother Res.2023, 37(10):4587-4606.
J Food Sci Technol.2019, 56(5):2712-2720
Processes2022, 10(10), 2008.
J Basic Clin Physiol Pharmacol.2016, 27(1):1-8
Plant Pathology2022, 13527
J Ethnopharmacol.2023, 317:116789.
Plant Cell Tiss Org2020, 1-16
Agriculture2022, 12(12), 2173.
Microchemical Journal2014, 203:110804.
Related and Featured Products
Biol Pharm Bull. 2005 Sep;28(9):1798-800.
7-hydroxy-3-(4-hydroxybenzyl)chroman and broussonin b: neurotrophic compounds, isolated from Anemarrhena asphodeloides BUNGE, function as proteasome inhibitors.[Pubmed:
16141565 ]
METHODS AND RESULTS:
The extract of Anemarrhenae Rhizoma (rhizomes of Anemarrhena asphodeloides BUNGE) showed neurotrophic activity toward rat pheochromocytoma (PC-12) cells. Bioassay-guided purification afforded four compounds, 2,6,4'-trihydroxy-4-methoxybenzophenone (1), 7-hydroxy-3-(4-hydroxybenzyl)chroman (2), Broussonin B (3), and cis-hinokiresinol (4).
CONCLUSIONS:
Compounds 1-3 induced neurite outgrowth in PC-12 cells at concentration of 50 microg/ml, while 4 was less active. In addition, compounds 2-4 showed moderate inhibitory activities against a chymotrypsin-like activity of the proteasome.
Bioorg Med Chem Lett. 2012 Apr 15;22(8):2760-3.
A new pancreatic lipase inhibitor from Broussonetia kanzinoki.[Pubmed:
22450131 ]
METHODS AND RESULTS:
A new phenolic compound, broussonone A (1) were isolated from the stem barks of Broussonetia kanzinoki (Moraceae), together with two diphenylpropanes, broussonin A (2), Broussonin B (3), two flavans, 7,4'-dihydroxyflavan (4), 3',7-dihydroxy-4'-methoxyflavan (5), and two flavones, 3,7-dihydroxy-4'-methoxyflavone (6), 3,7,3'-trihydroxy-4'-methoxyflavone (7).
CONCLUSIONS:
Compound 1 showed noncompetitive inhibitory activity on pancreatic lipase with an IC(50) of 28.4 μM. In addition, compounds 1-5 significantly inhibited adipocyte differentiation in 3T3-L1 cells as measured fat accumulation using Oil Red O assay.
Chemistry Letters,1980,3(3):339-340.
Broussonins A and B, new phytoalexins from diseased paper mulberry.[Reference:
WebLink]
METHODS AND RESULTS:
Isolation and structure elucidation of two phytoalexins (1 and 2), produced by diseased paper mulberry and designated as Broussonin A and Broussonin B, are described.
CONCLUSIONS:
These phytoalexins are characterized structurally by a 1,3-diphenylpropane skeleton.
Kakkalide
Catalog No: CFN95052
CAS No: 58274-56-9
Price: $260/10mg
1-O-galloyl-6-O-cinnamoylglucose
Catalog No: CFN95053
CAS No: 115746-69-5
Price: $338/5mg
Scutellarein-7-O-glucoside
Catalog No: CFN95082
CAS No: 26046-94-6
Price: $318/10mg
5,7,2',4'-Tetrahydroxy-8,3'-di(gamma,gamma-dimethylallyl)-isoflavanone
Catalog No: CFN95084
CAS No: 141846-47-1
Price: $413/5mg
1,3,6-Trihydroxy-2-methylanthraquinone 3-O-alpha-L-rhamnosyl-(1->2)-beta-D-glucoside
Catalog No: CFN95096
CAS No: 87686-88-2
Price: $318/10mg
Silychristin B
Catalog No: CFN95160
CAS No: 879325-58-3
Price: $318/5mg
Ginsenoside MC
Catalog No: CFN95232
CAS No: 175484-06-7
Price: $318/10mg
1-(3',5'-dimethoxy)phenyl-2-[4''-O-beta-D-glucopyranosyl (6->1)-O-alpha-L-rhamnopyranosyl]phenylethane
Catalog No: CFN95285
CAS No: 1338076-61-1
Price: $413/5mg
8-Hydroxypinoresinol-4'-O-beta-D-glucopyranoside
Catalog No: CFN95356
CAS No: 102582-69-4
Price: $318/5mg
5-Hydroxy-4a,8-dimethyl-3-methylen-decahydroazuleno[6,5-b]furan-2(3H)-on
Catalog No: CFN95522
CAS No: 114579-31-6
Price: $318/5mg
