Bernardioside A
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Eur J Pharmacol.2020, 889:173589.
J Agric Food Chem.2021, 69(46):14037-14047.
Processes2022, 10(10), 2008.
Toxicol In Vitro.2018, 52:94-105
Am J Chin Med.2023, 51(4):1019-1039.
J Agric Food Chem.2015, 63(44):9869-78
Appl Microbiol Biotechnol.2016, 100(9):3965-77
Int J Mol Sci.2024, 25(17):9730.
Anat Rec (Hoboken).2021, 304(2):323-332.
Phytochem Anal.2022, doi: 10.1002
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Journal of Natural Products, 2008, 71(5):828-835.
Perennisosides I−VII, Acylated Triterpene Saponins with Antihyperlipidemic Activities from the Flowers of Bellis perennis[Reference:
WebLink]
METHODS AND RESULTS:
The methanolic extract and its saponin fraction (methanol-eluted fraction) of the flowers of Bellis perennis were found to suppress serum triglyceride elevation in olive oil-treated mice. From the saponin fraction, seven new triterpene saponins, perennisosides I (1), II (2), III (3), IV (4), V (5), VI (6), and VII (7), were isolated together with four known saponins, bellidioside A (8), asterbatanoside D (9), bernardioside B 2 (10), and bellissaponin BS6 (11). The stereostructures of 1- 7 were elucidated on the basis of chemical and spectroscopic evidence.
CONCLUSIONS:
Among these saponins, perennisosides I (1) and II (2) showed inhibitory effects on serum triglyceride elevation at doses of 25-50 mg/kg, po.
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