Baohuoside VII
Baohuoside aglycone possesses cardioprotective effect in prevention of ischemia/ reperfusion injury and reduce the myocardial infraction, the mechnism is due to the reduction of the injury of free radicals. Baohuoside VII in vivo exhibits significant anti-osteoporosis activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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J.Mol. Catal. B Enzym., 2015, 122:141-6.
Biotransformation of major flavonoid glycosides in herb epimedii by the fungus Cunninghamella blakesleana[Reference:
WebLink]
METHODS AND RESULTS:
Biotransformation of icariin ( 1 ), epimedin C ( 2 ), epimedoside A ( 3 ), epimedin A ( 4 ) and epimidin B ( 5 ), five major components of E. koreanum , were performed by using Cunninghamella blakesleana . And they could be metabolized efficiently to icariside II ( 1a ), 2″- O -rhamnosylikarisoside II ( 2a ), epimedoside b ( 3a ), Baohuoside VII ( 4a ) and sagittatoside B ( 5a ) with high yields of 95.1%, 97.7%, 93.7%, 95.8% and 96.4%, respectively. And these transformed products as major forms of herb epimedii in vivo exhibited the more significant anti-osteoporosis activities.
CONCLUSIONS:
Our method could be applied for enriching these rare 04avonoids in herb epimedii, for further development of anti-osteoporosis medicines or functional foods.
