7,3',4'-Trihydroxy-3-benzyl-2H-chromene

7,3',4'-Trihydroxy-3-benzyl-2H-chromene
Product Name 7,3',4'-Trihydroxy-3-benzyl-2H-chromene
CAS No.: 1111897-60-9
Catalog No.: CFN99209
Molecular Formula: C16H14O4
Molecular Weight: 270.3 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Targets: XO
Source: The heartwoods of Caesalpinia sappan L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
7,3',4'-Trihydroxy-3-benzyl-2H-chromene is a potential xanthine oxidase inhibitor.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    To develop an HPLC method for In vitro screening of xanthine oxidase inhibitors.
    METHODS AND RESULTS:
    The activity of xanthine oxidase inhibitors was evaluated by the concentration of xanthine assayed by HPLC. The chromatographic conditions were as follows:column, Agilent SB-C18 (4.6 mm×250 mm, 5 μm); mobile phase, 0.02 mol·L-1 KH2PO4 (1% methanol); flow rate, 1.0 mL·min-1; detection wavelength, 254 nm; injection volume, 20 μL; column temperature, room temperature. Xanthine was perfectly separated from the other components under the selected chromatographic conditions. The xanthine oxidase inhibitory activity of 14 traditional Chinese medicines was evaluated by the above method. The 70% ethanol extracts of Quisqualis indica,Caesalpinia sappan,Polygonum cuspidatum and Paeonia suffruticosa showed significant activity with IC50 of 10. 04,8. 02,2. 06 and 1. 36 mg·mL- 1,respectively. Then,24 compounds isolated from C. sappan were evaluated by the above method. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene,3-deoxysappanone B,sappanchalcone and protosappanin A showed xanthine oxidase inhibitory activity.
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