5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone | CAS:98187-98-5

Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

LWT2020, 126:109313

Life (Basel).2023, 13(2):457.

Antioxidants (Basel).2020, 9(2):E120

Front Cell Dev Biol.2021, 9:764263.

Pharmaceuticals (Basel).2021, 14(7):633.

Vietnam J. Chemistry2022, 60(2):211-222

Phytomedicine.2019, 67:153159

Korean J. of Horticultural Sci. & Tech. 2017, 793-804

Free Radic Biol Med.2021, 166:104-115.

J Biochem Mol Toxicol.2017, 31(9)

Archives of Pharmacal Research,1987, 10 (4) :260-261.

Beziehung zwischen dem UV-Absorptionsmuster einiger Flavone und ihrer gegen L1210-Zellen cytotoxischen Aktivität[Reference: WebLink]

METHODS AND RESULTS:
The UV-pattern of several flavones, their cytotoxicities against L1210 cell and their Inhibiting effects on ATPase from the cell seem to be correlated. 5,2′-Dihydroxy-6,7,8,6′-tetramethoxyflavone (ED50=2.3 ug/ml) and 5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone (ED50=4.5 ug/ml), the most active flavones studied, have shown a narrow range of the absorbance ratio, Log εII/Log εI=1.073～1.109. They have inhibited the ATPase-activity to the greatest extent.
CONCLUSIONS:
These findings suggest that a certain angle between the flavone rings B and C plays an important role for the inhibition of the enzyme activity and thus the cytotoxicity.

Product Name	5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone
CAS No.:	98187-98-5
Catalog No.:	CFN92215
Molecular Formula:	C₁₈H₁₆O₈
Molecular Weight:	360.3 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Yellow powder
Targets:	ATPase
Source:	The roots of Scutellaria baicalensis Georgi
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: