5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone

5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone
Product Name 5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone
CAS No.: 98187-98-5
Catalog No.: CFN92215
Molecular Formula: C18H16O8
Molecular Weight: 360.3 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Yellow powder
Targets: ATPase
Source: The roots of Scutellaria baicalensis Georgi
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone (ED 50 =4.5 ug/ml ) shows cytotoxicity against L1210 cell and has inhibiting effects on ATPase from the cell.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Toxicol Res.2019, 35(4):371-387
  • ACS Omega2020, 5,33,20825-20830
  • Molecules.2023, 28(4):1785.
  • Antioxidants (Basel).2019, 8(8):E307
  • Biotechnology and Bioprocess Engineering2024, 29:1048-1060.
  • Research SPJ.2024, 0377.
  • J Liq Chromatogr R T2018, 41(12):761-769
  • Tumour Biol.2015, 36(12):9385-93
  • Toxicol Mech Methods.2021, 1-12.
  • Hindawi J of Food Biochemistry2023, P17:8883860
  • 5,7,3'-Trihydroxy-6,4',5'-trimethoxyflavone

    Catalog No: CFN90939
    CAS No: 78417-26-2
    Price: Inquiry(manager@chemfaces.com)
    3'-Hydroxy-5,7,4',5'-Tetramethoxyflavone

    Catalog No: CFN95397
    CAS No: 29976-51-0
    Price: $318/5mg
    Tricetin

    Catalog No: CFN70392
    CAS No: 520-31-0
    Price: $118/10mg
    Tricin

    Catalog No: CFN98841
    CAS No: 520-32-1
    Price: $258/10mg
    Salcolin A

    Catalog No: CFN95965
    CAS No: 1977557-69-9
    Price: $318/5mg
    Salcolin B

    Catalog No: CFN95966
    CAS No: 369390-52-3
    Price: $318/5mg
    Tricin 4'-O-(erythro-beta-guaiacylglyceryl)ether

    Catalog No: CFN95973
    CAS No: 1292294-32-6
    Price: $318/5mg
    Tricin 4'-O-(threo-beta-guaiacylglyceryl)ether

    Catalog No: CFN95993
    CAS No: 369390-51-2
    Price: $318/5mg
    4',5-Dihydroxy-3',5',6,7-tetramethoxyflavone

    Catalog No: CFN97322
    CAS No: 83133-17-9
    Price: Inquiry(manager@chemfaces.com)
    3',5-Dihydroxy-4',5',6,7-tetramethoxyflavone

    Catalog No: CFN99214
    CAS No: 111537-41-8
    Price: Inquiry(manager@chemfaces.com)
    Archives of Pharmacal Research,1987, 10 (4) :260-261.
    Beziehung zwischen dem UV-Absorptionsmuster einiger Flavone und ihrer gegen L1210-Zellen cytotoxischen Aktivität[Reference: WebLink]

    METHODS AND RESULTS:
    The UV-pattern of several flavones, their cytotoxicities against L1210 cell and their Inhibiting effects on ATPase from the cell seem to be correlated. 5,2′-Dihydroxy-6,7,8,6′-tetramethoxyflavone (ED50=2.3 ug/ml) and 5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone (ED50=4.5 ug/ml), the most active flavones studied, have shown a narrow range of the absorbance ratio, Log εII/Log εI=1.073~1.109. They have inhibited the ATPase-activity to the greatest extent.
    CONCLUSIONS:
    These findings suggest that a certain angle between the flavone rings B and C plays an important role for the inhibition of the enzyme activity and thus the cytotoxicity.
    Cordifolioside A

    Catalog No: CFN95040
    CAS No: 155179-20-7
    Price: $318/10mg
    Carasiphenol C

    Catalog No: CFN95045
    CAS No: 868168-04-1
    Price: $368/5mg
    Macrophylloside D

    Catalog No: CFN95113
    CAS No: 179457-69-3
    Price: $318/10mg
    Momordicoside X

    Catalog No: CFN95170
    CAS No: 1333321-50-8
    Price: $368/5mg
    (3S,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol

    Catalog No: CFN95195
    CAS No: 87095-75-8
    Price: $318/5mg
    5-Hydroxy-7,8-dimethoxy (2R)-flavanone-5-O-beta-D-glucopyranoside

    Catalog No: CFN95209
    CAS No: 942626-74-6
    Price: $318/10mg
    N-trans-p-Coumaroyltyrosine

    Catalog No: CFN95279
    CAS No: 77201-66-2
    Price: $318/10mg
    13(S)-Hydroxyoctadeca-9(Z),11(E)-dienoic acid (13-HODE)

    Catalog No: CFN95307
    CAS No: 18104-45-5
    Price: $318/10mg
    8-Epiloganin

    Catalog No: CFN95478
    CAS No: 79172-04-6
    Price: $318/20mg
    12beta-Acetoxy-7beta-hydroxy-3,11,15,23-tetraoxo-5alpha-lanosta-8,20-dien-26-oic acid

    Catalog No: CFN95515
    CAS No: 1245946-62-6
    Price: $318/5mg