4'-hydroxy-6,7,8,3'-tetramethoxyflavonol
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Chem Biodivers.2023, 20(12):e202301461.
Korean Herb. Med. Inf.2020, 8(2):205-213
Separations2023, 10(7), 411.
Processes2021, 9(11),2065.
Reprod Toxicol.2020, 96:1-10.
Iranian J. Pharm. Res.2021, 20(4):59-70
Int J Mol Sci.2022, 23(13):7115.
Pharmaceuticals (Basel).2021, 14(7):633.
Food Sci Biotechnol.2023, 32(7):997-1003.
J Pharm Biomed Anal.2017, 140:274-280
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PHYTOCHEM LETT, 2015.
Two new flavonols from flowers of Getonia floribunda Roxb.[Reference:
WebLink]
METHODS AND RESULTS:
Phytochemical investigation of the EtOAc and MeOH extracts from flowers of Getonia floribunda Roxb., a Thai herbal medicine, resulted in the isolation of two new flavonols, 4'-hydroxy-6,7,8,3'-tetramethoxyflavonol (1) and 4'-hydroxy-6,7,8-trimethoxyflavonol (2), along with a known pachypodol (3). Their structures were elucidated by spectroscopic methods including UV, IR, 1D and 2D NMR techniques and MS analysis.
CONCLUSIONS:
Compound 1 showed cytotoxicity against the oral cavity cancer (KB) cell line with an IC50 value of 8.99 +/- 2.00 mu g/ml. (C)
