4-O-Galloylbergenin
4-O-Galloylbergenin shows significant 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging activity with EC₅₀ 7.8 uM, it shows more antioxidant activity than the positive control vitamin C (EC₅₀ = 28.3 uM).
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Integr Med Res.2021, 10(3):100723.
Biochem Biophys Res Commun.2021, 534:802-807.
Phytother Res.2022, 10.1002:ptr.7626.
J Korean Med Ophthalmol Otolaryngol Dermatol2023, 36(1):21-39.
Nutrients.2022, 14(16):3393.
Biochem Systematics and Ecology2017, 11-18
mBio.2020, 11(3):e00686-20.
Eur J Neurosci.2021, 53(11):3548-3560.
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Nat Prod Res. 2013;27(14):1242-5
A new bergenin derivative from the rhizome of Ardisia gigantifolia.[Pubmed:
22991954]
METHODS AND RESULTS:
One new bergenin derivative, named 11-O-veratroylbergenin (1) along with five known bergenin derivatives, 11-O-(3'-O-methylgalloyl) bergenin (2), 11-O-syringylbergenin (3), 11-O-Galloylbergenin (4), 4-O-Galloylbergenin (5) and bergenin (6) were isolated from Ardisia gigantifolia Stapf. Their structures were established on the basis of spectroscopic analysis, especially by means of 1D, 2D-NMR and HR-ESIMS analyses.
CONCLUSIONS:
Compounds 2, 4 and 5 showed significant 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging activity with EC₅₀ 9.7, 9.0 and 7.8 μmol L(-1), respectively. They showed more antioxidant activity than the positive control vitamin C (EC₅₀ = 28.3 μmol L(-1)).
