1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one | CAS:207792-17-4

1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one shows strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation of human whole blood.

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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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J. Mater. Life Sci.2024, 3:2:78-87

Biomed Pharmacother.2019, 116:108987

Enzyme Microb Technol.2022, 153:109941.

Biomedicines.2024, 12(3):495.

Evid Based Complement Alternat Med.2022, 9767292,2.

Nutrients.2019, 11(4):E936

iScience.2020, 23(2):100849.

J Control Release.2024, 375:300-315.

Arch Pharm Res.2015, 38(6):1080-9

Mutlu Yanic S, Ates EG. JOTCSA.2023, 10(4);893-902.

J Nat Prod. 1998 Jan;61(1):142-4.

A new antiplatelet diarylheptanoid from Alpinia blepharocalyx.[Pubmed: 9461664 ]

METHODS AND RESULTS:
A new diarylheptanoid, 1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one (1), along with seven other known compounds, were isolated from the seeds of Alpinia blepharocalyx.
CONCLUSIONS:
Of these, compounds 1 and 3 showed strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation of human whole blood. Compound 3 also strongly inhibited ristocetin-induced platelet aggregation. Structures of these compounds were elucidated by spectroscopic and chemical means.

Product Name	1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one
CAS No.:	207792-17-4
Catalog No.:	CFN96210
Molecular Formula:	C₁₉H₁₈O₄
Molecular Weight:	310.4 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Yellow powder
Targets:	PAFR
Source:	The roots of Curcuma longa L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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