Platyphyllonol
Platyphyllonol-5-xylopyranoside is moderately active against KBNP-0028 (H9N2) avian influenza virus as compared with zanamivir.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Molecules.2018, 23(7):E1659
Cell Rep.2020, 32(11):108158.
Chem Biol Interact.2022, 368:110248.
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China Pharmacy2015, 26(27)
Molecules2022, 27(11):3606.
J Ethnopharmacol.2019, 244:112074
Int Immunopharmacol.2024, 141:112906.
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Bioorg. Med. Chem. Lett. , 2010, 20(3):1000-3.
Anti-influenza diarylheptanoids from the bark of Alnus japonica.[Pubmed:
20045319 ]
METHODS AND RESULTS:
This study to investigate anti-influenza components from the bark of Alnus japonica resulted in the isolation of two rare acylated diarylheptanoids, named oregonoyl A (5) and oregonoyl B (6), along with nine known compounds (1-4 and 7-11). Their structures were elucidated on the basis of extensive spectroscopic and chemical methods.
CONCLUSIONS:
Antiviral testing of compounds 1-11 against KBNP-0028 (H9N2) avian influenza virus showed that platyphyllone (10) was strongly active, and Platyphyllonol-5-xylopyranoside (9) was moderately active against KBNP-0028 as compared with the positive control, zanamivir, respectively.
