Hepatotoxicity

beta-Asarone
Catalog No: CFN98870

beta-Asarone has neuroprotection, anti-tumor, anthelmintic, anti-inflammary, and anticoagulant effects, it can afford a beneficial inhibition on both mRNA and protein expression of Bad, Bax, and cleavage of caspases 9 in rat hippocampus following intrahippocampal injections of Abeta (1-42).beta-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in SAMP8 mice. beta Asarone can cause liver and cardiac damages, it also has reproductive toxicity.

Deoxycalyciphylline B
Catalog No: CFN97061

Deoxycalyciphylline B exhibits hepatic toxicity. Deoxycalyciphylline B and Methyl homosecodaphniphyllate show different inhibitory effects on thephenoloxidase (PO) of Spodoptera exigua (Hbner) and the inhibitor concentrations leading to 50% (IC50) activity lost are estimated to be 2.439 mmol.L-1 for deoxycalyciphyllineB and 0.879mmol.L-1 for methyl homosecodaphniphyllate,respectively.

Pseudotropine
Catalog No: CFN00217

Pseudotropine can cause hepatic necrosis and gastritis with ulceration or erosions.

Supinine
Catalog No: CFN00238

Supinine has hepatotoxic activity.

Diosbulbin D
Catalog No: CFN97140

Diosbulbin D shows direct toxic effect on hepatocytes, the mechanism could be associated with oxidative stress.