Pseudotropine
Pseudotropine can cause hepatic necrosis and gastritis with ulceration or erosions.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Vet. Hum. Toxicol., 1995, 37(5):452-4
Toxicity of field bindweed (Convolvulus arvensis) to mice.[Pubmed:
8592835]
The effects of feeding high and low doses of field bindweed (Convolvulus arvensis) to mice were investigated. Bindweed contains several alkaloids, including Pseudotropine, and lesser amounts of tropine, tropinone, and meso-cuscohygrine.
METHODS AND RESULTS:
Mice fed bindweed exclusively died or were euthanized after 4-7 d and had severe hepatic necrosis and gastritis with ulceration or erosions. Mice fed low doses of bindweed along with standard laboratory mouse diet for 6 or 8 w had no clinical disease or gross lesions on necropsy examination but did have histologic lesions of mild multifocal hepatitis and gastritis.
Tetrahedron Letters Volume 25, Issue 44, 1984, Pages 5091–5094
A new synthetic route to tropane alkaloids. Pseudotropine and tropacocaine[Reference:
WebLink]
Pseudotropine and tropacocaine have been synthesized by a facile route involving the [4 + 2] nitroso cycloaddition followed by internal SN2 displacement.
