Supinine | CAS:551-58-6 | Manufacturer ChemFaces

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Hepatotoxic pyrrolizidine alkaloids in Emilia sonchifolia from Taiwan[Reference: WebLink]

Emilia sonchifolia (L.) DC. (Lilac tasselflower, Zi Bei Cao) is used in Asian countries for food or medicinal purposes. We have investigated the hepatotoxic pyrrolizidine alkaloids (PAs) contained in E. sonchifolia. The objective was to determine profile and quantity of the PAs in E. sonchifolia samples that were collected from several towns in Taiwan.
METHODS AND RESULTS:
Pyrrolizidine alkaloids were isolated and purified from the aqueous acid extracts by use of strong cation exchange-solid phase extraction (SCX-SPE). Alkaloid extracts were analyzed using gas–chromatography mass spectrometry (GC–MS). Eleven PAs of two types were identified in E. sonchifolia (by type): (1) retronecine bases, senecionine, seneciphylline and integerrimine; (2) otonecine bases, senkirkine, otosenine, neosenkirkine, petasitenine, acetylsenkirkine, desacetyldoronine, acetylpetasitenine, and doronine. Quantification of the individual PAs was determined by six-point linear regression curves in the range of 25–400 μg/mL of senkirkine and senecionine. The PAs were found in all plant organs of E. sonchifolia. Senkirkine was the major PA identified with concentrations up to 53.8 μg/g of dry herb. The average total PA concentration varied from a low of 33.3 μg/g to a high of 93.9 μg/g dry herb.
CONCLUSIONS:
This study will provide important information to public consumers regarding the health risk of PA-containing E. sonchifolia.

Product Name	Supinine
CAS No.:	551-58-6
Catalog No.:	CFN00238
Molecular Formula:	C₁₅H₂₅NO₄
Molecular Weight:	283.37 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The herbs of Heliotropium indicum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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