Hepatotoxicity

Echimidine
Catalog No: CFN00254

Echimidine, a major hepatotoxic dehydropyrrolizidine alkaloid produced by E. plantagineum, in the honey (780 ng/g) and in the subsequent mead samples (236–540 ng/mL). Echimidine-N-Oxide has antifungal activity.

Symlandine
Catalog No: CFN00261

Symlandine, 7-acetylintermedine, and 7-acetyllycopsamine are pyrrolizidine alkaloids, isolated from comfrey, can produce hepatotoxicity in livestock and humans and carcinogenicity in experimental animals.

Heliotrine
Catalog No: CFN00270

The pyrrolizidine alkaloid Heliotrine interferes with reporter signals derived from GAL4-based nuclear receptor transactivation assays by a mechanism independent of luciferase enzyme inhibition. Acute hepatitis induced by Heliotrine is accompanied by uncoupling of oxidative phosphorylation in liver mitochondria.

7-Acetylintermedine
Catalog No: CFN00286

7-Acetylintermedine, 7-acetyllycopsamine, and symlandine are pyrrolizidine alkaloids, isolated from comfrey, can produce hepatotoxicity in livestock and humans and carcinogenicity in experimental animals.

7-Acetyllycopsamine
Catalog No: CFN00288

7-Acetyllycopsamine exhibits antibacterial effects with a MIC of 1.7 mg/ml in E. coli. 7-Acetyllycopsamine, 7-acetylintermedine, and symlandine are pyrrolizidine alkaloids, isolated from comfrey, can produce hepatotoxicity in livestock and humans and carcinogenicity in experimental animals.