Clivorine
Catalog No: CFN00355
Clivorine itself has direct toxicity on HEK293 cells, and phosphorylated JNK may play some role in counteracting the toxicity of Clivorine on HEK293 cells. It has anti-proliferative function in L-02 cells may be due to its inducing cell apoptosis with independent of p53 protein. Clivorine induces hepatotoxicity and acute liver injury, which can be protected by quercetin, trolox and epidermal growth factor via inhibiting apoptotic cell death and ameliorating oxidative stress injury.