Cytotoxic

Myricanol
Catalog No: CFN98430

Myricanol can elicit growth inhibitory and cytotoxic effects on lung cancer cells, it can significantly decelerate tumor growth in vivo by inducing apoptosis.

Pachypodol
Catalog No: CFN98433

Pachypodol has antibacterial and antifungal activities against Bacillus subtilis, Staphylococcus aureus, Staphylococcus faecalis, Echerichia coli, Pseudomonas aeruginosa, Candida albicans, Candida krusei and Candida galabrata. Pachypodol has cytotoxic potential , it can inhibit the growth of CaCo 2 colon cancer cell line in vitro. Pachypodol exhibits anti-emetic effects.

(-)-Catechin gallate(CG)
Catalog No: CFN98504

(-)-Catechin gallate is a minor constituent in green tea catechins, it inhibits the activity of COX-1 and COX-2 enzymes. Catechin gallate (IC50=53 microM) shows cytotoxicity against the colorectal adenocarcinoma cell line HCT116, it also exhibits strong anti-proliferative and anti-inflammatory activities on pancreatic ductal adenocarcinoma (PDAC) cells. Catechin 3-gallate is a good inhibitor of maltase, with IC50 values of 62 uM, it inhibits both α-glucosidases and rabbit glycogen phosphorylase (GP) in vitro and in cell culture, would contribute to the protection or improvement of type 2 diabetes.

7-Oxodehydroabietinol
Catalog No: CFN98438

7-Oxodehydroabietinol shows moderate cytotoxicity against a human lung carcinoma cell line. It also exhibits significant antibacterial activity against gram (±) bacteria.

Cephalomannine
Catalog No: CFN98518

Cephalomannine is a taxol derivative with antitumor, antiproliferative properties, it shows cytotoxicity in human glial and neuroblastoma cell-lines.