Cytotoxic

Ceanothic acid
Catalog No: CFN98063

Ceanothic acid derivatives show cytotoxic effect against OVCAR-3 and HeLa cancer cell lines.

18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one
Catalog No: CFN98065

18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one shows moderate cytotoxicity against a human lung carcinoma cell line.

1-Decarboxy-3-oxo-ceanothic acid
Catalog No: CFN98072

1-Decarboxy-3-oxo-ceanothic acid shows in vitro cytotoxic activity in a human ovarian adenocarcinoma cell line, the cytotoxic effect is mediated, at least in part, by the induction of apoptosis. It shows cytotoxic against OVCAR-3 and HeLa cancer cell lines, with an IC50 of 2.8 and 6.6 microg/mL, respectively, and an IC50 of 11.3 microg/mL against normal cell line FS-5.

20(R)-Protopanaxatriol
Catalog No: CFN99980

20(R)-Protopanaxatriol shows anti-hyperglycaemic, and anti-cancer activities.Protopanaxatriol has inhibitory effects on the enzyme catalytic activities of cyclooxygenases-1 and -2 (COX-1 and -2).

23-deoxojessic acid
Catalog No: CFN98074

23-Deoxojessic acid possesses strong cytotoxicity towards highly liver metastatic murine colon 26-L5 carcinoma cells, with ED50 values equal to or less than 6 microM.