Cytotoxic

Cylindramide
Catalog No: CFN00112

Cylindramide is cytotoxic against B16 melanoma cells with an IC50 of 0.8 ug/m, it shows promising antiproliferative activity against several tumour cell lines. (+)-Cylindramide has anti-microbial properties.

Discodermide
Catalog No: CFN00114

Discodermide has antifungal and cytotoxic activities.

Aristolactam BIII
Catalog No: CFN98904

Aristolactam BIII possesses anti-platelet aggregation activity in vitro, it also shows significant cytotoxic activity (IC50 values < 4 microg/mL) against P-388, HT-29 and A549 cell lines in vitro.

2-Oxopomolic acid
Catalog No: CFN98920

2-Oxopomolic acid shows cytotoxic activity, it shows a significant decrease in intracellular melanin content in B16-F10 cells, and in culture media melanin. 2-Oxopomolic acid shows radical-scavenging activities similar to that of the reference antioxidant alpha-tocopherol (vitamin E).

Myriceric acid B
Catalog No: CFN98931

Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41 and can serve as a lead compound for developing novel anti-HIV-1 drug. Myriceric acid B scavenges DPPH free radicals with IC50 value of 21.8 uM, it inhibits aromatase activity with IC50 value of 6.8 uM, it also exhibits cytotoxic activity towards the MOLT-3 cell line with IC50 values of 3.9 uM.