Cytotoxic

Coronalolide
Catalog No: CFN98317

Coronalolide shows significant cytotoxic activities in P-388 cell line, it also displays significant anti-HIV activities in the HIV-1RT assay. Coronalolide and coronalolide methyl ester show broad cytotoxic activity against a panel of human cancer cell lines.

Erysotrine
Catalog No: CFN98336

Erysotrine does not show cytotoxic activity by itself, but exhibits significant cytotoxicity when combines with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). (+)-Erysotrine shows potent dosedependant antifeedant activity at concentrations ≥100 ppm.

Ervamycine
Catalog No: CFN98338

11-Methoxytabersonine(Ervamycine) exhibits inhibitory effects against five human cancer cell lines , with IC(50) values comparable to those of cisplatin and vinorelbine.

Dihydrodehydrodiconiferyl alcohol
Catalog No: CFN98342

Dihydrodehydrodiconiferyl alcohol exhibits in vitro cytotoxicity in various cancer cell lines. It may be useful candidates for developing therapeutic agents for the prevention and treatment of hepatic fibrosis.

Reynosin
Catalog No: CFN98344

Reynosin has hepatoprotective, and anti-inflammatory effects, it has protective effect against dopamine-induced neuronal cell death, which may be due to the reciprocal up-regulation of E6-associated protein and down-regulation of α-synuclein protein expression. Reynosin exhibits a dose-dependent inhibition on CINC-1 induction in LPS-stimulated NRK-52E cells, where 50% of inhibitory effect was shown at the concentration of about 1 microM. Reynosin also has strong anti-mycobactericidal activity, with a minimal bactericidal concentration (MBC) of 128ug/mL against the H37Rv, 366-2009 and 104-2010 Mtb strains and a minimal inhibitory concentration (MIC) of 64, 64, 128, 128 and 128ug/mL against the H37Rv, 104-2010, 63-2009, 366-2009 and 430-2010 Mtb strains, respectively.