Antimalaric

Digitolutein
Catalog No: CFN92109

Digitolutein has inhibition on the growth of Plasmodium falciparum in vitro.

Eurycomalactone
Catalog No: CFN92129

Eurycomalactone as a potent NF-κB inhibitor with the IC50 value of less than 1 uM. It shows antiplasmodial activity against Gombak A isolate. Eurycomalactone displays potent activity against all the tested cell lines [colon 26-L5 carcinoma (IC50 = 0.70 microM), B16-BL6 melanoma (IC50 = 0.59 microM), Lewis lung carcinoma (IC50 = 0.78 microM), and a human lung A549 adenocarcinoma (IC50 = 0.73 microM)].

Methyltanshinonate
Catalog No: CFN92148

Methyltanshinonate shows antiplasmodial and antitrypanosomal activities. It may have antioxidative activity.

Isochamaejasmine
Catalog No: CFN92150

Isochamaejasmine has inhibition of NF-kappaB activation, which could reverse the anti-apoptotic effect; it induces apoptosis in leukemia cells by inhibiting the activity of Bcl-2 family proteins, providing evidence for further studying the underlying anti-cancer mechanism of S. chamaejasme L. Isochamaejasmine shows antiplasmodial activity, with an IC(50) of 7.3+/-3.8 microM, but the selectivity was rather limited.

Ferruginol
Catalog No: CFN92178

Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic, cardioprotective, anticancer, anti-oxidative and anti-inflammatory activities, it can induce apoptosis in non-small cell lung cancer (NSCLC) cells. Ferruginol has antimicrobial and antifungal activities against wood-rot fungi (basidiomycetes), can cause cellular dysfunction and damage, lead to growth inhibition and autophagic cell death of fungi.