Antimalaric

Acetylursolic acid
Catalog No: CFN97219

Acetylursolic acid shows significant cytotoxic activities, and shows suppression of the SOS-inducing activity of mutagenic heterocyclic amine, Trp-P-1. 3β-Acetylursolic acid can reduce parasitaemia against Plasmodium berghei.

Quassin
Catalog No: CFN97246

Quassin has female anti-fertility properties, possibly acting via inhibition of estrogen secretion. Quassin alters the immunological patterns of murine macrophages through generation of nitric oxide to exert antileishmanial activity. It also exhibits P. falciparum inhibitory activity (IC50=0.06 micro g/ml, 0.15 micro M). Quassin possesses anti-anaemic property, it can significantly increase red blood cell count, pack cell volume and haemoglobin concentration.

Dehydrocrebanine
Catalog No: CFN97265

Dehydrocrebanine has strong activity against promyelocytic leukemia cells (HL-60) with an IC50 of 2.14 ug/mL. It also shows potent antimalarial activity with an IC50 value of 70 ng/ml.

Artemisinic acid
Catalog No: CFN97276

Artemisinic acid, is the immediate precursor of the semi-synthesis artemisinin, could be a cost-effective, environmentally friendly, high-quality and reliable source of artemisinin. Artemisinic acid has a variety of pharmacological activity, such as antimalarial, anti-tumor, antipyretic, antibacterial, allelopathy and anti-adipogenesis effects. Artemisinic acid is a regulator of adipocyte differentiation and C/EBP δ expression, it inhibits adipogenic differentiation of hAMSCs through reduced expression of C/EBP δ; it inhibits melanogenesis through downregulation of C/EBP α-dependent expression of HMG-CoA reductase gene.

Anisofolin A
Catalog No: CFN97327

Anisofolin A has promising antimalarial activity (IC50 4.39 ± 0.25 uM). It has promising antimycobacterium activity [IC50 4.50 ± 0.75 uM (3.31 ug/mL)] against M. tuberculosis H37Ra and at 100 ug/mL, shows 55.6 % inhibition of M. bovis.