Anticancer

Echinacoside
Catalog No: CFN98105

Echinacoside is a natural polyphenolic compound, has various kinds of pharmacological activities, such as anti-senescence, anti-hypoxia, anti-cancer, anti-osteoporosis, antioxidative, anti-inflammatory, neuroprotective, hepatoprotective, nitric oxide radical-scavenging and vasodilative ones. Echinacoside can improve the hematopoietic function of bone marrow in 5-FU-induced myelosuppression mice, it induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1. Echinacoside inhibits cytochrome c release and caspase-3 activation caused by ensuing rotenone exposure via activating Trk-extracellular signal-regulated kinase (ERK) pathway in neuronal cells.

3,8-Di-O-methylellagic acid
Catalog No: CFN98217

3,3'-Di-O-methylellagic acid reveals moderate antibacterial activity, it also shows strong DPPH radical scavenging activities with SC50 of 123.3 ug/mL. It has a lower capacity of stimulating murine peritoneal macrophages to release nitric oxide and tumoural-alpha necrose factor. 3,3'-Di-O-methylellagic acid may be a useful as pharmacological agent for the treatment of neurodegenerative diseases.

Falcarindiol
Catalog No: CFN98220

Falcarindiol has antimutagenic, neuroprotective, antifungal, anti-bacterial, and anticancer activities, it could be potentially used in food manufactures and cosmetology as preservative agents and biopesticides, or in medicine as new antibiotics. Falcarindiol has protective effects against CCl(4) toxicity, in part, the effects might be explained by anti-lipid peroxidation activity associated with the induction of the GSTs including GSTA4.

Ocotillone
Catalog No: CFN98221

Ocotillone has potent antibacterial activity against Gram-negative bacteria, P. aeruginosa and S. typhimurium, that are without hemolytic activity, whereas it has weak antimicrobial activity against Gram-positive bacteria and fungi. Ocotillone shows only weak inhibitory activity against MCF-7 and NCI-H460 cells but moderate activity against A375-C5 cells.

Epifriedelanol acetate
Catalog No: CFN98223

Epifriedelanol exhibits antibacterial activities. It also can reduce cellular senescence in human primary cells and may be used to develop dietary supplements or cosmetics that modulate tissue aging or aging-associated diseases. Epifriedelanol and friedelin possess promising antioxidant activity, and they are active against the two cancer cells (human T4 lymphoblastoid (CEM-SS) and human cervical (HeLa) cancer cells) with IC50 values ranging from 3.54 to11.45 ug/ml.