Anticancer

Geniposidic acid
Catalog No: CFN98337

Geniposidic acid is an effective anticancer and radioprotection agent, used to treat inflammation, jaundice and hepatic disorders. It has anti-atherosclerotic effects, can protect vascular endothelium and reverse plaque formation in an atherosclerotic model. Geniposidic acid has effects on the expression of MRP2 and BSEP in BRL-3A cells after FXR gene silencing mediated by si RNA.

Ervamycine
Catalog No: CFN98338

11-Methoxytabersonine(Ervamycine) exhibits inhibitory effects against five human cancer cell lines , with IC(50) values comparable to those of cisplatin and vinorelbine.

7-Geranyloxy-6-methoxycoumarin
Catalog No: CFN98348

7-Geranyloxy-6-methoxycoumarin shows significant cytotoxicity against three cell lines (A549, SMMC-7721 and BALL-1).

Byakangelicol
Catalog No: CFN98167

Byakangelicol exhibits hepatoprotective activities on tacrine-induced cytotoxicity in Hep G2 cells, with EC(50) values of 112.7 +/- 5.35 microM. Byakangelicol may have therapeutic potential as an anti-inflammatory drug on airway inflammation, it can inhibit IL-1beta-induced PGE2 release in A549 cells; this inhibition may be mediated by suppression of COX-2 expression and the activity of COX-2 enzyme, it also can inhibit P-gp expressed. Byakangelicol shows a significant inhibition on the proliferation of cultured human tumor cells.

20(R)-Ginsenoside Rg3
Catalog No: CFN98170

20(R)-Ginsenoside Rg3 has anticarcinogenic, neuroprotective, anti-aging and antifatigue activities, it has a wide spectrum of targets including caspase-3, MMP-2, MMP-9,HIF-1a,VEGF,IL-1,IL-6 and TNF-a.