Anticancer

Stigmasterol glucoside
Catalog No: CFN98000

Stigmasterol glucoside, a constituent of Adenanthera pavonina seed and leaf, may be a plant anticancer agent.

Atractylenolide I
Catalog No: CFN99944

Atractylenolide I, a TLR4-antagonizing agent, shows a wide spectrum of pharmacological activities such as anti-inflammatory, digestion promoting,significant antitumor, and antioxidant effects. It ameliorates sepsis syndrome,liver and kidney functions by reduction of pro-inflammatory cytokines and LPS.

Atractylenolide II
Catalog No: CFN99945

Atractylenolide II has antiinflammatory activity, it can inhibit platelets activities and thrombus formation. Atractylenolide II has cytotoxic/apoptotic effects may via p38 activation ,ERK and Akt inactivation, p53 dependent, it also has antimelanoma effect by inhibiting STAT3 signalling.

Bufalin
Catalog No: CFN99947

Bufalin a major digoxin-like immunoreactive component of the Chinese medicine Chan Su; has been shown to exert a potential for anticancer activity against various human cancer cell lines in vitro. Bufalin is a potent small-molecule inhibitor of the steroid receptor coactivators steroid receptor coactivator (SRC)-3 and SRC-1, it also as a potentially broad-spectrum small-molecule inhibitor for cancer. Bufalin can partly reverse the MDR of K562/VCR cells, with a possible mechanism of down-regulating MRP1 expression and activating apoptosis pathway by altering Bcl-xL/Bax ratio.

Methyllucidone
Catalog No: CFN98012

Methyllucidone may have a neuroprotective potential via inhibition of neurotoxic microglial activation implicated in neurodegeneration.It can strongly inhibit the growth of human cancer cells and colon tumor xenografted in nude mice, the anti-tumor effects are further confirmed with caspase-3 activation and degradation of PARP. Methyllucidone shows 85% antifungal activity at 50 against the disease wheat leaf rust.